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Literature DB >> 12527658

Drug eluting stents: are human and animal studies comparable?

R Virmani¹, F D Kolodgie, A Farb, A Lafont.

Abstract

Animal models of stenting probably predict human responses as the stages of healing are remarkably similar. What is characteristically different is the temporal response to healing, which is substantially prolonged in humans. The prevention of restenosis in recent clinical trials of drug eluting stents may represent a near absent or incomplete phase of intimal healing. Continued long term follow up of patients with drug eluting stents for major adverse cardiac events and angiographic restenosis is therefore imperative.

Entities: Disease Species

Mesh：

Substances：
Drug Implants

Year: 2003 PMID： 12527658 PMCID： PMC1767527 DOI： 10.1136/heart.89.2.133

Source DB: PubMed Journal: Heart ISSN： 1355-6037 Impact factor: 5.994

27 in total

1. Dose-response effects of 32P radioactive stents in an atherosclerotic porcine coronary model.

Authors: A J Carter; D Scott; L Bailey; T Hoopes; R Jones; R Virmani
Journal: Circulation Date: 1999-10-05 Impact factor: 29.690

Review 2. A paradigm for restenosis based on cell biology: clues for the development of new preventive therapies.

Authors: J S Forrester; M Fishbein; R Helfant; J Fagin
Journal: J Am Coll Cardiol Date: 1991-03-01 Impact factor: 24.094

3. Lack of neointimal proliferation after implantation of sirolimus-coated stents in human coronary arteries: a quantitative coronary angiography and three-dimensional intravascular ultrasound study.

Authors: J E Sousa; M A Costa; A Abizaid; A S Abizaid; F Feres; I M Pinto; A C Seixas; R Staico; L A Mattos; A G Sousa; R Falotico; J Jaeger; J J Popma; P W Serruys
Journal: Circulation Date: 2001-01-16 Impact factor: 29.690

4. Long-term effects of intracoronary beta-radiation in balloon- and stent-injured porcine coronary arteries.

Authors: G L Kałuza; A E Raizner; W Mazur; D G Schulz; J M Buergler; L F Fajardo; F O Tio; N M Ali
Journal: Circulation Date: 2001-04-24 Impact factor: 29.690

5. First clinical experience with a paclitaxel derivate-eluting polymer stent system implantation for in-stent restenosis: immediate and long-term clinical and angiographic outcome.

Authors: Francesco Liistro; Goran Stankovic; Carlo Di Mario; Takuro Takagi; Alaide Chieffo; Shahram Moshiri; Matteo Montorfano; Mauro Carlino; Carlo Briguori; Paolo Pagnotta; Remo Albiero; Nicola Corvaja; Antonio Colombo
Journal: Circulation Date: 2002-04-23 Impact factor: 29.690

6. Intravascular ultrasound findings in the multicenter, randomized, double-blind RAVEL (RAndomized study with the sirolimus-eluting VElocity balloon-expandable stent in the treatment of patients with de novo native coronary artery Lesions) trial.

Authors: Patrick W Serruys; Muzaffer Degertekin; Kengo Tanabe; Alexandre Abizaid; J Edouardo Sousa; Antonio Colombo; Giulio Guagliumi; William Wijns; Wietze K Lindeboom; Jurgen Ligthart; Pim J de Feyter; Marie-Claude Morice
Journal: Circulation Date: 2002-08-13 Impact factor: 29.690

7. Proliferation in primary and restenotic coronary atherectomy tissue. Implications for antiproliferative therapy.

Authors: E R O'Brien; C E Alpers; D K Stewart; M Ferguson; N Tran; D Gordon; E P Benditt; T Hinohara; J B Simpson; S M Schwartz
Journal: Circ Res Date: 1993-08 Impact factor: 17.367

8. Twenty-eight-day efficacy and phamacokinetics of the sirolimus-eluting stent.

Authors: Bruce D Klugherz; Gerard Llanos; Warren Lieuallen; Gregory A Kopia; George Papandreou; Pallassana Narayan; Brett Sasseen; Steven J Adelman; Robert Falotico; Robert L Wilensky
Journal: Coron Artery Dis Date: 2002-05 Impact factor: 1.439

9. Restenosis and the proportional neointimal response to coronary artery injury: results in a porcine model.

Authors: R S Schwartz; K C Huber; J G Murphy; W D Edwards; A R Camrud; R E Vlietstra; D R Holmes
Journal: J Am Coll Cardiol Date: 1992-02 Impact factor: 24.094

10. Morphological predictors of restenosis after coronary stenting in humans.

Authors: Andrew Farb; Deena K Weber; Frank D Kolodgie; Allen P Burke; Renu Virmani
Journal: Circulation Date: 2002-06-25 Impact factor: 29.690

52 in total

Review 1. Drug-eluting stents for cardiovascular disorders.

Authors: Juan F Granada; Grzegorz L Kaluza; Albert Raizner
Journal: Curr Atheroscler Rep Date: 2003-07 Impact factor: 5.113

Review 2. The future of drug eluting stents.

Authors: R R Anis; K R Karsch
Journal: Heart Date: 2005-10-10 Impact factor: 5.994

Review 3. In stent restenosis: bane of the stent era.

Authors: A K Mitra; D K Agrawal
Journal: J Clin Pathol Date: 2006-03 Impact factor: 3.411

Review 4. The importance of the endothelium in atherothrombosis and coronary stenting.

Authors: Fumiyuki Otsuka; Aloke V Finn; Saami K Yazdani; Masataka Nakano; Frank D Kolodgie; Renu Virmani
Journal: Nat Rev Cardiol Date: 2012-05-22 Impact factor: 32.419

5. Nitinol Carbofilm coated stents for peripheral applications: study in the porcine model.

Authors: M Prunotto; C Isaia; M A Gatti; E Monari; E Pasquino; M Galloni
Journal: J Mater Sci Mater Med Date: 2005-12 Impact factor: 3.896

6. Comparison of early vascular morphological changes between bioresorbable poly-L-lactic acid scaffolds and metallic stents in porcine iliac arteries.

Authors: Yasuhito Sekimoto; Hideaki Obara; Kentaro Matsubara; Naoki Fujimura; Hirohisa Harada; Yuko Kitagawa
Journal: Organogenesis Date: 2017-01-19 Impact factor: 2.500