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52 in total

1. Functional evidence for active site location of tetrameric thymidylate synthase X at the interphase of three monomers.

Authors: Damien Leduc; Sébastien Graziani; Gerard Lipowski; Christophe Marchand; Pierre Le Maréchal; Ursula Liebl; Hannu Myllykallio
Journal: Proc Natl Acad Sci U S A Date: 2004-04-27 Impact factor: 11.205

2. Trapping of an intermediate in the reaction catalyzed by flavin-dependent thymidylate synthase.

Authors: Tatiana V Mishanina; Eric M Koehn; John A Conrad; Bruce A Palfey; Scott A Lesley; Amnon Kohen
Journal: J Am Chem Soc Date: 2012-02-24 Impact factor: 15.419

3. A fast chemoenzymatic synthesis of [11C]-N5,N10-methylenetetrahydrofolate as a potential PET tracer for proliferating cells.

Authors: Muhammad Saeed; Timothy J Tewson; Colbin E Erdahl; Amnon Kohen
Journal: Nucl Med Biol Date: 2012-02-01 Impact factor: 2.408

9. 5,10-Methylene-5,6,7,8-tetrahydrofolate conformational transitions upon binding to thymidylate synthase: molecular mechanics and continuum solvent studies.

Authors: Adam Jarmuła; Piotr Cieplak; William R Montfort
Journal: J Comput Aided Mol Des Date: 2005-02 Impact factor: 3.686

Review 10. Relationship of femtosecond-picosecond dynamics to enzyme-catalyzed H-transfer.

Authors: Christopher M Cheatum; Amnon Kohen
Journal: Top Curr Chem Date: 2013

Lessons and conclusions from dissecting the mechanism of a bisubstrate enzyme: thymidylate synthase mutagenesis, function, and structure.

1. Functional evidence for active site location of tetrameric thymidylate synthase X at the interphase of three monomers.

2. Trapping of an intermediate in the reaction catalyzed by flavin-dependent thymidylate synthase.

3. A fast chemoenzymatic synthesis of [11C]-N5,N10-methylenetetrahydrofolate as a potential PET tracer for proliferating cells.

4. Hydride transfer versus hydrogen radical transfer in thymidylate synthase.

5. The structure of the TrmE GTP-binding protein and its implications for tRNA modification.

6. A remote mutation affects the hydride transfer by disrupting concerted protein motions in thymidylate synthase.

7. Role of Y94 in proton and hydride transfers catalyzed by thymidylate synthase.

8. The general base in the thymidylate synthase catalyzed proton abstraction.

9. 5,10-Methylene-5,6,7,8-tetrahydrofolate conformational transitions upon binding to thymidylate synthase: molecular mechanics and continuum solvent studies.

Review 10. Relationship of femtosecond-picosecond dynamics to enzyme-catalyzed H-transfer.