Literature DB >> 1252498

Intraction of aminoacyl-tRNA synthetases with ribosomes and ribosomal subunits.

H Graf.   

Abstract

Salt-washed ribosomes from rabbit reticulocytes stimulate seven partially purified aminoacyl-tRNA synthetases up to threefold: arginyl-, alanyl-, isoleucyl-, lysyl-, methionyl-, phenylalanyl- and valyl-tRNA synthetase. Both isolated subunits but not total ribosomal RNA show the stimulation. The increase in synthetase activity is also found in a highly purified Escherichia coli system employing homogenous (E. coli)phenyl-alanyl-tRNA synthetase and (E. coli)- tRNAPhe. The biological significance of the stimulation is discussed.

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Year:  1976        PMID： 1252498     DOI： 10.1016/0005-2787(76)90023-x

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  8 in total

1.  Channeling of aminoacyl-tRNA for protein synthesis in vivo.

Authors:  B S Negrutskii; M P Deutscher
Journal:  Proc Natl Acad Sci U S A       Date:  1991-06-01       Impact factor: 11.205

2.  A sequestered pool of aminoacyl-tRNA in mammalian cells.

Authors:  B S Negrutskii; M P Deutscher
Journal:  Proc Natl Acad Sci U S A       Date:  1992-04-15       Impact factor: 11.205

3.  Existence of two forms of rat liver arginyl-tRNA synthetase suggests channeling of aminoacyl-tRNA for protein synthesis.

Authors:  P Sivaram; M P Deutscher
Journal:  Proc Natl Acad Sci U S A       Date:  1990-05       Impact factor: 11.205

Review 4.  Higher eukaryotic aminoacyl-tRNA synthetases in physiologic and pathologic states.

Authors:  C V Dang; C V Dang
Journal:  Mol Cell Biochem       Date:  1986-08       Impact factor: 3.396

5.  A channeled tRNA cycle during mammalian protein synthesis.

Authors:  R Stapulionis; M P Deutscher
Journal:  Proc Natl Acad Sci U S A       Date:  1995-08-01       Impact factor: 11.205

6.  Subcellular distribution and properties of rabbit liver aminoacyl-tRNA synthetases under myocardial ischemia.

Authors:  L L Ivanov; Z Martinkus; O V Kharchenko; S Sara; L Lukoshevichius; A Prashkevichius; A V El'skaya
Journal:  Mol Cell Biochem       Date:  1993-08-25       Impact factor: 3.396

7.  Supramolecular organization of the mammalian translation system.

Authors:  B S Negrutskii; R Stapulionis; M P Deutscher
Journal:  Proc Natl Acad Sci U S A       Date:  1994-02-01       Impact factor: 11.205

8.  Heavy and light forms of some aminoacyl-tRNA synthetases in fraction X, microsomes and cytosol of rabbit liver.

Authors:  H Berbeć; A Paszkowska; T Borkowski
Journal:  Mol Cell Biochem       Date:  1984-06       Impact factor: 3.396
  8 in total

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