| Literature DB >> 12520055 |
Jie Chen1, John B Anderson, Carol DeWeese-Scott, Natalie D Fedorova, Lewis Y Geer, Siqian He, David I Hurwitz, John D Jackson, Aviva R Jacobs, Christopher J Lanczycki, Cynthia A Liebert, Chunlei Liu, Thomas Madej, Aron Marchler-Bauer, Gabriele H Marchler, Raja Mazumder, Anastasia N Nikolskaya, Bachoti S Rao, Anna R Panchenko, Benjamin A Shoemaker, Vahan Simonyan, James S Song, Paul A Thiessen, Sona Vasudevan, Yanli Wang, Roxanne A Yamashita, Jodie J Yin, Stephen H Bryant.
Abstract
Three-dimensional structures are now known within most protein families and it is likely, when searching a sequence database, that one will identify a homolog of known structure. The goal of Entrez's 3D-structure database is to make structure information and the functional annotation it can provide easily accessible to molecular biologists. To this end, Entrez's search engine provides several powerful features: (i) links between databases, for example between a protein's sequence and structure; (ii) pre-computed sequence and structure neighbors; and (iii) structure and sequence/structure alignment visualization. Here, we focus on a new feature of Entrez's Molecular Modeling Database (MMDB): Graphical summaries of the biological annotation available for each 3D structure, based on the results of automated comparative analysis. MMDB is available at: http://www.ncbi.nlm.nih.gov/Entrez/structure.html.Mesh:
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Year: 2003 PMID: 12520055 PMCID: PMC165533 DOI: 10.1093/nar/gkg086
Source DB: PubMed Journal: Nucleic Acids Res ISSN: 0305-1048 Impact factor: 16.971