Literature DB >> 12511580

Alzheimer disease therapy: can the amyloid cascade be halted?

Todd E Golde1.   

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Year:  2003        PMID: 12511580      PMCID: PMC151845          DOI: 10.1172/JCI17527

Source DB:  PubMed          Journal:  J Clin Invest        ISSN: 0021-9738            Impact factor:   14.808


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  102 in total

Review 1.  Plaque busters: strategies to inhibit amyloid formation in Alzheimer's disease.

Authors:  C Soto
Journal:  Mol Med Today       Date:  1999-08

Review 2.  Open peer commentary regarding Abeta immunization and CNS inflammation by Pasinetti et al.

Authors:  Pritam Das; Todd E Golde
Journal:  Neurobiol Aging       Date:  2002 Sep-Oct       Impact factor: 4.673

3.  Aspartyl protease inhibitor pepstatin binds to the presenilins of Alzheimer's disease.

Authors:  G Evin; R A Sharples; A Weidemann; F B Reinhard; V Carbone; J G Culvenor; R M Holsinger; M F Sernee; K Beyreuther; C L Masters
Journal:  Biochemistry       Date:  2001-07-27       Impact factor: 3.162

4.  Ibuprofen suppresses plaque pathology and inflammation in a mouse model for Alzheimer's disease.

Authors:  G P Lim; F Yang; T Chu; P Chen; W Beech; B Teter; T Tran; O Ubeda; K H Ashe; S A Frautschy; G M Cole
Journal:  J Neurosci       Date:  2000-08-01       Impact factor: 6.167

5.  Rates of global and regional cerebral atrophy in AD and frontotemporal dementia.

Authors:  D Chan; N C Fox; R Jenkins; R I Scahill; W R Crum; M N Rossor
Journal:  Neurology       Date:  2001-11-27       Impact factor: 9.910

6.  Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP.

Authors:  J Lewis; D W Dickson; W L Lin; L Chisholm; A Corral; G Jones; S H Yen; N Sahara; L Skipper; D Yager; C Eckman; J Hardy; M Hutton; E McGowan
Journal:  Science       Date:  2001-08-24       Impact factor: 47.728

7.  A decamer duplication in the 3' region of the BRI gene originates an amyloid peptide that is associated with dementia in a Danish kindred.

Authors:  R Vidal; T Revesz; A Rostagno; E Kim; J L Holton; T Bek; M Bojsen-Møller; H Braendgaard; G Plant; J Ghiso; B Frangione
Journal:  Proc Natl Acad Sci U S A       Date:  2000-04-25       Impact factor: 11.205

8.  Presenilin-1 and -2 are molecular targets for gamma-secretase inhibitors.

Authors:  D Seiffert; J D Bradley; C M Rominger; D H Rominger; F Yang; J E Meredith; Q Wang; A H Roach; L A Thompson; S M Spitz; J N Higaki; S R Prakash; A P Combs; R A Copeland; S P Arneric; P R Hartig; D W Robertson; B Cordell; A M Stern; R E Olson; R Zaczek
Journal:  J Biol Chem       Date:  2000-11-03       Impact factor: 5.157

9.  Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model.

Authors:  L M Refolo; B Malester; J LaFrancois; T Bryant-Thomas; R Wang; G S Tint; K Sambamurti; K Duff; M A Pappolla
Journal:  Neurobiol Dis       Date:  2000-08       Impact factor: 5.996

10.  Statins and the risk of dementia.

Authors:  H Jick; G L Zornberg; S S Jick; S Seshadri; D A Drachman
Journal:  Lancet       Date:  2000-11-11       Impact factor: 79.321

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  36 in total

Review 1.  Neurodegeneration: what is it and where are we?

Authors:  Serge Przedborski; Miquel Vila; Vernice Jackson-Lewis
Journal:  J Clin Invest       Date:  2003-01       Impact factor: 14.808

Review 2.  Apoptotic mechanisms in Alzheimer neurofibrillary degeneration: cause or effect?

Authors:  Dennis W Dickson
Journal:  J Clin Invest       Date:  2004-07       Impact factor: 14.808

3.  Inhibition of phosphodiesterase-4 reverses memory deficits produced by Aβ25-35 or Aβ1-40 peptide in rats.

Authors:  Yu-Fang Cheng; Chuang Wang; Huan-Bing Lin; Yun-Feng Li; Ying Huang; Jiang-Ping Xu; Han-Ting Zhang
Journal:  Psychopharmacology (Berl)       Date:  2010-07-17       Impact factor: 4.530

4.  Changing the course of Alzheimer's disease: anti-amyloid disease-modifying treatments on the horizon.

Authors:  Daniel D Christensen
Journal:  Prim Care Companion J Clin Psychiatry       Date:  2007

5.  BRI2 (ITM2b) inhibits Abeta deposition in vivo.

Authors:  Jungsu Kim; Victor M Miller; Yona Levites; Karen Jansen West; Craig W Zwizinski; Brenda D Moore; Fredrick J Troendle; Maralyssa Bann; Christophe Verbeeck; Robert W Price; Lisa Smithson; Leilani Sonoda; Kayleigh Wagg; Vijayaraghavan Rangachari; Fanggeng Zou; Steven G Younkin; Neill Graff-Radford; Dennis Dickson; Terrone Rosenberry; Todd E Golde
Journal:  J Neurosci       Date:  2008-06-04       Impact factor: 6.167

Review 6.  Neuroprotective strategies in Alzheimer's disease.

Authors:  Frank M Longo; Stephen M Massa
Journal:  NeuroRx       Date:  2004-01

7.  5-Lipoxygenase gene disruption reduces amyloid-beta pathology in a mouse model of Alzheimer's disease.

Authors:  Omidreza Firuzi; Jiamin Zhuo; Cinzia M Chinnici; Thomas Wisniewski; Domenico Praticò
Journal:  FASEB J       Date:  2007-11-12       Impact factor: 5.191

8.  Modular synthesis of heparan sulfate oligosaccharides for structure-activity relationship studies.

Authors:  Sailaja Arungundram; Kanar Al-Mafraji; Jinkeng Asong; Franklin E Leach; I Jonathan Amster; Andre Venot; Jeremy E Turnbull; Geert-Jan Boons
Journal:  J Am Chem Soc       Date:  2009-12-02       Impact factor: 15.419

9.  MCP-1 involvement in glial differentiation of neuroprogenitor cells through APP signaling.

Authors:  Emmanuel George Vrotsos; Pappachan E Kolattukudy; Kiminobu Sugaya
Journal:  Brain Res Bull       Date:  2009-01-29       Impact factor: 4.077

10.  MER5101, a novel Aβ1-15:DT conjugate vaccine, generates a robust anti-Aβ antibody response and attenuates Aβ pathology and cognitive deficits in APPswe/PS1ΔE9 transgenic mice.

Authors:  Bin Liu; Jeffrey L Frost; Jing Sun; Hongjun Fu; Stephen Grimes; Peter Blackburn; Cynthia A Lemere
Journal:  J Neurosci       Date:  2013-04-17       Impact factor: 6.167

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