Literature DB >> 12510721

Our experience with perfluorohexyloctane (F6H8) as a temporary endotamponade in vitreoretinal surgery.

M I Stefaniotou1, M V Aspiotis, G D Kitsos, Chr D Kalogeropoulos, I C Asproudis, K G Psilas.   

Abstract

PURPOSE: To evaluate the use of F6H8 as a temporary endotamponade for complicated and special cases of retinal detachment instead of silicone oil.
METHODS: We have used F6H8 with 14 patients since February 1999. Eight suffered from rhegmatogenous retinal detachment (RRD) with multiple tears located inferiorly. Three presented inferior traction retinal detachment (TRD) under silicone oil, two suffered from ocular trauma with inferior TRD, and one had idiopathic macular hole. The substance was introduced into the eye after pars plana vitrectomy and membrane peeling if needed, and we tried to introduce as much as possible.
RESULTS: With F6H8 the retina was easily reattached in all cases, like with perfluorocarbon liquids. The postoperative view was very good. F6H8 was removed in all cases after 3-8 weeks. Anatomical success was achieved in 12 out of 14 eyes. Two eyes presented severe PVR. F6H8 entered the anterior chamber in 4 cases, but no corneal complications occurred. In one case there was a marked IOP rise due to an anterior block, treated with superior iridotomy. In two cases retinal detachment (RD) occurred in the upper part and was treated with additional surgery, F6H8 removal and silicone oil injection.
CONCLUSIONS: F6H8 seems to be a promising tamponade agent for special cases of RD.

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Year:  2002        PMID: 12510721     DOI: 10.1177/112067210201200612

Source DB:  PubMed          Journal:  Eur J Ophthalmol        ISSN: 1120-6721            Impact factor:   2.597


  8 in total

1.  A pilot study on the use of silicone oil-RMN3 as heavier-than-water endotamponade agent.

Authors:  Stanislao Rizzo; Federica Genovesi-Ebert; Claudia Belting; Andrea Vento; Federica Cresti
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2005-06-28       Impact factor: 3.117

2.  Influence on membrane-mediated cell activation by vesicles of silicone oil or perfluorohexyloctane.

Authors:  Norbert Kociok; Claudia Gavranic; Bernd Kirchhof; Antonia M Joussen
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2004-10-27       Impact factor: 3.117

3.  [Perfluorohexyloctane as internal tamponade in patients with complicated retinal detachment. Results after 6 months].

Authors:  H Gerding; A Kolck
Journal:  Ophthalmologe       Date:  2004-03       Impact factor: 1.059

4.  Tamponade efficiency of perfluorohexyloctane and silicone oil solutions in a model eye chamber.

Authors:  C Wetterqvist; D Wong; R Williams; T Stappler; E Herbert; S Freeburn
Journal:  Br J Ophthalmol       Date:  2004-05       Impact factor: 4.638

5.  The combined use of perfluorohexyloctane (F6H8) and silicone oil as an intraocular tamponade in the treatment of severe retinal detachment.

Authors:  Stanislao Rizzo; Federica Genovesi-Ebert; Claudia Belting
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2006-03-21       Impact factor: 3.117

Review 6.  Heavy silicone oil and intraocular inflammation.

Authors:  Francesco Morescalchi; Ciro Costagliola; Sarah Duse; Elena Gambicorti; Barbara Parolini; Barbara Arcidiacono; Mario R Romano; Francesco Semeraro
Journal:  Biomed Res Int       Date:  2014-07-08       Impact factor: 3.411

Review 7.  Vitreous Substitutes as Drug Release Systems.

Authors:  André Schulz; Peter Szurman
Journal:  Transl Vis Sci Technol       Date:  2022-09-01       Impact factor: 3.048

Review 8.  Vitreous substitutes: the present and the future.

Authors:  Simone Donati; Simona Maria Caprani; Giulia Airaghi; Riccardo Vinciguerra; Luigi Bartalena; Francesco Testa; Cesare Mariotti; Giovanni Porta; Francesca Simonelli; Claudio Azzolini
Journal:  Biomed Res Int       Date:  2014-05-04       Impact factor: 3.411

  8 in total

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