Literature DB >> 16550400

The combined use of perfluorohexyloctane (F6H8) and silicone oil as an intraocular tamponade in the treatment of severe retinal detachment.

Stanislao Rizzo1, Federica Genovesi-Ebert, Claudia Belting.   

Abstract

BACKGROUND: The purpose of this study was to investigate the combined use of perfluorohexyloctane (F6H8) and 1,000-centistoke silicone oil as a long-term intraocular tamponade in the treatment of complicated retinal detachment.
METHODS: Sixty consecutive eyes affected by complicated retinal detachment with (1) retinal breaks of the lower two quadrants and severe proliferative vitreoretinopathy, (2) inferior giant retinal tear, (3) penetrating trauma or (4) choroidal detachment underwent pars plana vitrectomy using a combined internal tamponade of F6H8 and silicone oil. The double filling (DF) was removed after 40-50 days. The anatomical outcome and the complications due to the DF are reported.
RESULTS: Retinal reattachment was achieved in all but one patient. Thirty-eight (63%) eyes needed further surgery with silicone oil tamponade. Silicone oil was successfully removed in 22 eyes. Sixteen (27%) eyes had retained silicone oil at the last follow-up examination. One eye showed persistent retinal detachment despite further surgery. Main complications of the DF were recurrent retinal detachment of the upper retina in six (10%) eyes and membrane formation in 25 (42%) eyes.
CONCLUSIONS: A combined internal tamponade of F6H8 and silicone oil may be a useful tool in the treatment of complicated retinal detachment involving the lower quadrants of the retina.

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Year:  2006        PMID: 16550400     DOI: 10.1007/s00417-006-0317-3

Source DB:  PubMed          Journal:  Graefes Arch Clin Exp Ophthalmol        ISSN: 0721-832X            Impact factor:   3.117


  26 in total

1.  The effect of simultaneous internal tamponade on fluid compartmentalization and its relationship to cell proliferation.

Authors:  V De Molfetta; F Bottoni; P Arpa; P Vinciguerra; S Zenoni
Journal:  Retina       Date:  1992       Impact factor: 4.256

2.  Experimental studies of the combined use of vitreous substitutes of high and low specific gravity.

Authors:  J R Sparrow; A Jayakumar; M Berrocal; E Ozmert; S Chang
Journal:  Retina       Date:  1992       Impact factor: 4.256

3.  Long-term vitreous replacement in primates with intravitreal Vitreon or Vitreon plus silicone.

Authors:  G A Peyman; M D Conway; K F Soike; L C Clark
Journal:  Ophthalmic Surg       Date:  1991-11

4.  Perfluorohexyloctane as a long-term vitreous tamponade in the experimental animal. Experimental perfluorohexyloctane substitution.

Authors:  D Zeana; J Becker; R Kuckelkorn; B Kirchhof
Journal:  Int Ophthalmol       Date:  1999       Impact factor: 2.031

5.  Semifluorinated alkanes--a new class of compounds with outstanding properties for use in ophthalmology.

Authors:  H Meinert; T Roy
Journal:  Eur J Ophthalmol       Date:  2000 Jul-Sep       Impact factor: 2.597

6.  Tamponade properties of double-filling with perfluorohexyloctane and silicone oil in a model eye chamber.

Authors:  Edward Herbert; Theodor Stappler; Carolina Wetterqvist; Rachel Williams; David Wong
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2003-12-18       Impact factor: 3.117

7.  Experimental vitreous replacement with perfluorotributylamine.

Authors:  S Chang; N J Zimmerman; T Iwamoto; R Ortiz; D Faris
Journal:  Am J Ophthalmol       Date:  1987-01-15       Impact factor: 5.258

8.  The classification of retinal detachment with proliferative vitreoretinopathy.

Authors: 
Journal:  Ophthalmology       Date:  1983-02       Impact factor: 12.079

9.  Experimental long-term vitreous replacement with purified and nonpurified perfluorodecalin.

Authors:  M Velikay; A Wedrich; U Stolba; P Datlinger; Y Li; S Binder
Journal:  Am J Ophthalmol       Date:  1993-11-15       Impact factor: 5.258

10.  Perfluoroperhydrophenanthrene (Vitreon) as a short-term vitreous substitute after complex vitreoretinal surgery.

Authors:  T M Tanji; G A Peyman; N J Mehta; C M Millsap
Journal:  Ophthalmic Surg       Date:  1993-10
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  6 in total

1.  Surgical results of heavy silicone oil HWS-45 3000 as internal tamponade for inferior retinal detachment with PVR: a pilot study.

Authors:  Stanislao Rizzo; Maria Chiara Romagnoli; Federica Genovesi-Ebert; Claudia Belting
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2010-09-15       Impact factor: 3.117

2.  Combined use of perfluorohexyloctane and silicone oil as intraocular tamponade: an in vitro study.

Authors:  Luciano Lepori; Enrico Matteoli; Andrea Spanedda; Federica Genovesi-Ebert; Stanislao Rizzo
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2005-06-28       Impact factor: 3.117

3.  Intraocular perfluorodecalin and silicone oil tamponade (double filling) in the management of complicated retinal detachment: functional and anatomical outcomes using small-gauge surgery.

Authors:  Emma Clara Zanzottera; Alessandro Marchese; Francesco Bandello; Michele Coppola
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2021-09-22       Impact factor: 3.535

Review 4.  The concept of heavy tamponades-chances and limitations.

Authors:  Antonia M Joussen; David Wong
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2008-06-11       Impact factor: 3.117

5.  Pars plana vitrectomy for primary rhegmatogenous retinal detachment.

Authors:  Stephen G Schwartz; Harry W Flynn
Journal:  Clin Ophthalmol       Date:  2008-03

6.  F6H8 as an Intraoperative Tool and F6H8/Silicone Oil as a Postoperative Tamponade in Inferior Retinal Detachment with Inferior PVR.

Authors:  Gian Marco Tosi; Davide Marigliani; Tommaso Bacci; Napoleone Romeo; Angelo Balestrazzi; Gianluca Martone; Tomaso Caporossi
Journal:  J Ophthalmol       Date:  2014-01-02       Impact factor: 1.909

  6 in total

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