BACKGROUND: The World Health Organization (WHO) ICD-10 Primary Health Care (PHC) Guidelines for Diagnosis and Management of Mental Disorders (1996) have not been evaluated in a pragmatic randomised controlled trial (RCT). AIMS: To evaluate the effect of local adaptation and dissemination of the guidelines. METHOD: Pragmatic, pair-matched, cluster RCT involving 30 practices. RESULTS: Guideline practices were less sensitive but more specific in identifying morbidity, but these differences were not significant. Guideline patients did not differ from usual-care patients on 12-item General Health Questionnaire scores at 3-month follow-up or in the proportion who were still cases. There were no significant differences in secondary outcomes. CONCLUSIONS: Attempts to influence clinician behaviour through a process of adaptation and extension of guidelines are unlikely to change detection rates or outcomes.
RCT Entities:
BACKGROUND: The World Health Organization (WHO) ICD-10 Primary Health Care (PHC) Guidelines for Diagnosis and Management of Mental Disorders (1996) have not been evaluated in a pragmatic randomised controlled trial (RCT). AIMS: To evaluate the effect of local adaptation and dissemination of the guidelines. METHOD: Pragmatic, pair-matched, cluster RCT involving 30 practices. RESULTS: Guideline practices were less sensitive but more specific in identifying morbidity, but these differences were not significant. Guideline patients did not differ from usual-care patients on 12-item General Health Questionnaire scores at 3-month follow-up or in the proportion who were still cases. There were no significant differences in secondary outcomes. CONCLUSIONS: Attempts to influence clinician behaviour through a process of adaptation and extension of guidelines are unlikely to change detection rates or outcomes.
Authors: Vimal K Sharma; Peter Lepping; Anthony G P Cummins; John R M Copeland; Rashmi Parhee; Patricia Mottram Journal: World Psychiatry Date: 2004-06 Impact factor: 49.548
Authors: Andor E Simon; Sabrina Jegerlehner; Thomas Müller; Katja Cattapan-Ludewig; Peter Frey; Marcus Grossenbacher; Erich Seifritz; Daniel Umbricht Journal: Br J Gen Pract Date: 2010-09 Impact factor: 5.386
Authors: Anne Dezetter; X Briffault; R Bruffaerts; R De Graaf; J Alonso; H H König; J M Haro; G de Girolamo; G Vilagut; V Kovess-Masféty Journal: Soc Psychiatry Psychiatr Epidemiol Date: 2012-05-31 Impact factor: 4.328
Authors: Vimal K Sharma; Peter Lepping; Murali Krishna; Shazia Durrani; John R M Copeland; Patricia Mottram; Rashmi Parhee; Bennett Quinn; Steven Lane; Anthony Cummins Journal: Br J Gen Pract Date: 2008-06 Impact factor: 5.386