Literature DB >> 12502528

The Na+/Ca2+ exchange molecule: an overview.

Kenneth D Philipson1, Debora A Nicoll, Michela Ottolia, Beate D Quednau, Hannes Reuter, Scott John, Zhiyong Qiu.   

Abstract

An overview of the molecular physiology of the Na(+)/Ca(2+) exchanger is presented. This includes information on the variety of exchangers that have been described and their regulatory properties. Molecular insight is most detailed for the cardiac Na(+)/Ca(2+) exchanger (NCX1). Parts of the NCS1 molecule involved in regulation and ion transport have been elucidated, and initial information on the topology and structure is available.

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Year:  2002        PMID: 12502528     DOI: 10.1111/j.1749-6632.2002.tb04708.x

Source DB:  PubMed          Journal:  Ann N Y Acad Sci        ISSN: 0077-8923            Impact factor:   5.691


  39 in total

Review 1.  Development and application of Na+/Ca2+ exchange inhibitors.

Authors:  Takahiro Iwamoto; Satomi Kita
Journal:  Mol Cell Biochem       Date:  2004-04       Impact factor: 3.396

2.  Return of calcium: manipulating intracellular calcium to prevent cardiac pathologies.

Authors:  Yibin Wang; Joshua I Goldhaber
Journal:  Proc Natl Acad Sci U S A       Date:  2004-04-12       Impact factor: 11.205

3.  Allosteric activation of sodium-calcium exchange by picomolar concentrations of cadmium.

Authors:  Hoa Dinh Le; Alexander Omelchenko; Larry V Hryshko; Alexandra Uliyanova; Madalina Condrescu; John P Reeves
Journal:  J Physiol       Date:  2004-12-20       Impact factor: 5.182

Review 4.  [Reverse remodeling of the intracellular Ca(2+)-homeostasis: new concepts of pathophysiology and therapy of heart failure].

Authors:  Klara Brixius; Konrad F Frank; Birgit Bölck; Felix Hoyer; Robert H G Schwinger
Journal:  Wien Med Wochenschr       Date:  2006-04

5.  Electrophysiological demonstration of Na+/Ca2+ exchange in bovine articular chondrocytes.

Authors:  Julio C Sánchez; Trevor Powell; Henry M Staines; Robert J Wilkins
Journal:  Biorheology       Date:  2006       Impact factor: 1.875

6.  STIM2 is a feedback regulator that stabilizes basal cytosolic and endoplasmic reticulum Ca2+ levels.

Authors:  Onn Brandman; Jen Liou; Wei Sun Park; Tobias Meyer
Journal:  Cell       Date:  2007-12-28       Impact factor: 41.582

Review 7.  Proximal nephron.

Authors:  Jia L Zhuo; Xiao C Li
Journal:  Compr Physiol       Date:  2013-07       Impact factor: 9.090

Review 8.  Modulation of the cardiac Na+-Ca2+ exchanger by cytoplasmic protons: Molecular mechanisms and physiological implications.

Authors:  Kyle Scranton; Scott John; Ariel Escobar; Joshua I Goldhaber; Michela Ottolia
Journal:  Cell Calcium       Date:  2019-12-11       Impact factor: 6.817

9.  Crystallization and preliminary X-ray crystallographic analysis of Ca2+-free primary Ca2+-sensor of Na+/Ca2+ exchanger.

Authors:  Masashi Mima; Chika Kawai; Kumsun Paku; Koji Tomoo; Toshimasa Ishida; Shigeru Sugiyama; Hiroyoshi Matsumura; Tomoya Kitatani; Hiroshi Y Yoshikawa; Syou Maki; Hiroaki Adachi; Kazufumi Takano; Satoshi Murakami; Tsuyoshi Inoue; Yusuke Mori; Satomi Kita; Takahiro Iwamoto
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2008-11-28

10.  Inhibition of beta-cell sodium-calcium exchange enhances glucose-dependent elevations in cytoplasmic calcium and insulin secretion.

Authors:  Kevin S C Hamming; Daniel Soliman; Nicola J Webster; Gavin J Searle; Laura C Matemisz; David A Liknes; Xiao-Qing Dai; Thomas Pulinilkunnil; Michael J Riedel; Jason R B Dyck; Patrick E Macdonald; Peter E Light
Journal:  Diabetes       Date:  2010-04-22       Impact factor: 9.461

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