Literature DB >> 12502043

Ultrasound cylindrical phased array for transoesophageal thermal therapy: initial studies.

David Melodelima1, Cyril Lafon, Frederic Prat, Alain Birer, Dominique Cathignol.   

Abstract

This work was undertaken to investigate the feasibility of constructing a cylindrical phased array composed of 64 elements spread around the periphery (OD 10.6 mm) for transoesophageal ultrasound thermotherapy. The underlying operating principle of this applicator is to rotate a plane ultrasound beam electronically. For this purpose, eight adjacent transducers were successively excited with appropriate delay times so as to generate a plane wave. The exposure direction was changed by exciting a different set of eight elements. For these feasibility studies, we used a cylindrical prototype (OD 10.6 mm) composed of 16 elementary transducers distributed over a quarter of the cylinder, all operating at 4.55 MHz. The active part was mechanically reinforced by a rigid damper structure behind the transducers. It was shown that an ultrasound field similar to that emitted by a plane transducer could be generated. Ex vivo experiments on pig's liver demonstrated that the ultrasound beam could be accurately rotated to generate sector-based lesions to a suitable depth (up to 19 mm). Throughout these experiments, exposures lasting 20 s were delivered at an acoustic intensity of 17 W cm(-2). By varying the power from exposure to exposure, the depth of the lesion at different angles could be controlled.

Entities:  

Mesh:

Substances:

Year:  2002        PMID: 12502043     DOI: 10.1088/0031-9155/47/23/306

Source DB:  PubMed          Journal:  Phys Med Biol        ISSN: 0031-9155            Impact factor:   3.609


  4 in total

1.  64-element intraluminal ultrasound cylindrical phased array for transesophageal thermal ablation under fast MR temperature mapping: an ex vivo study.

Authors:  D Melodelima; R Salomir; C Mougenot; C Moonen; D Cathignol
Journal:  Med Phys       Date:  2006-08       Impact factor: 4.071

2.  Modeling of Interstitial Ultrasound Ablation for Continuous Applicator Rotation With MR Validation.

Authors:  Katie Y Gandomi; Paulo A W G Carvalho; Matthew Tarasek; Eric W Fiveland; Chitresh Bhushan; Emery Williams; Paul Neubauer; Zhanyue Zhao; Julie Pilitsis; Desmond Yeo; Christopher J Nycz; Everette Burdette; Gregory S Fischer
Journal:  IEEE Trans Biomed Eng       Date:  2021-05-21       Impact factor: 4.756

3.  Treatment of esophageal tumors using high intensity intraluminal ultrasound: first clinical results.

Authors:  David Melodelima; Frederic Prat; Jacques Fritsch; Yves Theillere; Dominique Cathignol
Journal:  J Transl Med       Date:  2008-06-05       Impact factor: 5.531

4.  Low-intensity continuous ultrasound triggers effective bisphosphonate anticancer activity in breast cancer.

Authors:  Sophie Tardoski; Jacqueline Ngo; Evelyne Gineyts; Jean-Paul Roux; Philippe Clézardin; David Melodelima
Journal:  Sci Rep       Date:  2015-11-18       Impact factor: 4.379

  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.