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Literature DB >> 12499216

Penetration of fosfomycin into inflammatory lesions in patients with cellulitis or diabetic foot syndrome.

F J Legat¹, A Maier, P Dittrich, P Zenahlik, T Kern, S Nuhsbaumer, M Frossard, W Salmhofer, H Kerl, M Müller.

Abstract

We investigated the distribution of the broad-spectrum antibiotic fosfomycin in infected soft tissue of patients with uncomplicated cellulitis of the lower extremities or diabetic foot infection using in vivo microdialysis. Our findings suggest that fosfomycin exhibits good and similar penetration into the fluid in the interstitial space in inflamed and noninflamed soft tissue in patients.

Entities: Chemical Disease Species

Mesh：

Substances：
Fosfomycin

Year: 2003 PMID： 12499216 PMCID： PMC148983 DOI： 10.1128/AAC.47.1.371-374.2003

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

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