Literature DB >> 12497008

Adenocarcinoma of the prostate: an expensive way to die.

N Y Piper1, L Kusada, R Lance, J Foley, J Moul, T Seay.   

Abstract

The costs of radical prostatectomy and radiation therapy for localized carcinoma of the prostate are well known, the costs of terminal care for men with metastatic disease less so. We sought to determine the costs of terminal care incurred with prostate cancer in the last year of life. A retrospective chart review was conducted at five military medical centers identifying 32 patients who had died from prostate cancer from 1995 to 1997. The data investigated were: duration of metastatic disease, days hospitalized in the last year of life, palliative procedures (surgery or radiation), chemotherapy and need for transfusions. The mean duration of symptomatic metastatic disease was 3.4 y. The mean duration of hospitalization in the last year of life was 19 days. Seven patients (22%) required channel transurethral resection of the prostate (TURP). Three patients (9%) required either percutaneous nephrostomies or stenting. The mean number of transfusions required was 5.4. Eighteen patients (56%) underwent bilateral simple orchiectomy (BSO), 14 (44%) used LHRH agonists and 11 (34%) used anti-androgens. The mean total cost of hospitalization, studies, outpatient visits to physicians, palliative procedures and hormonal therapy was US dollars 24660 in the last year of life. Comparatively, the cost of radical prostatectomy is US dollars 12250 and three-dimensional conformal radiation therapy is US dollars 13823. Our estimation of costs due to metastatic disease is at best an underestimation. Men dying of prostate cancer incur significant costs in the last year of life. Based upon recent epidemiological data the cost of death due to prostate cancer in the US is over three quarters of a billion dollars a year.

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Year:  2002        PMID: 12497008     DOI: 10.1038/sj.pcan.4500565

Source DB:  PubMed          Journal:  Prostate Cancer Prostatic Dis        ISSN: 1365-7852            Impact factor:   5.554


  10 in total

1.  Individualized strategy for dosing luteinizing hormone-releasing hormone agonists for androgen-independent prostate cancer: identification of outcomes and costs.

Authors:  Jennifer A Wagmiller; Jennifer J Griggs; Andrew W Dick; Deepak M Sahasrabudhe
Journal:  J Oncol Pract       Date:  2006-03       Impact factor: 3.840

2.  [Radical prostatectomy for men aged <56 years with prostate cancer. Cost of illness analysis].

Authors:  K Herkommer; T A Fuchs; R E Hautmann; B G Volkmer
Journal:  Urologe A       Date:  2005-10       Impact factor: 0.639

3.  Under Treatment of Prostate Cancer in Rural Locations.

Authors:  Avinash Maganty; Lindsay M Sabik; ZhaoJun Sun; Kirsten Y Eom; Jie Li; Benjamin J Davies; Bruce L Jacobs
Journal:  J Urol       Date:  2019-08-20       Impact factor: 7.450

4.  Reducing prostate cancer racial disparity: evidence for aggressive early prostate cancer PSA testing of African American men.

Authors:  Isaac J Powell; Fawn D Vigneau; Cathryn H Bock; Julie Ruterbusch; Lance K Heilbrun
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2014-05-06       Impact factor: 4.254

5.  Cost effectiveness of risk-prediction tools in selecting patients for immediate post-prostatectomy treatment.

Authors:  Valentina Bayer Zubek; Andre Konski
Journal:  Mol Diagn Ther       Date:  2009       Impact factor: 4.074

6.  Desquamation is a novel phenomenon for collective prostate epithelial cell deletion after castration.

Authors:  Rafaela Rosa-Ribeiro; Guilherme Oliveira Barbosa; Fabiana Kühne; Hernandes F Carvalho
Journal:  Histochem Cell Biol       Date:  2013-10-09       Impact factor: 4.304

7.  Cost-effectiveness analysis of stereotactic body radiation therapy versus intensity-modulated radiation therapy: an emerging initial radiation treatment option for organ-confined prostate cancer.

Authors:  Joseph C Hodges; Yair Lotan; Thomas P Boike; Rhonda Benton; Alyson Barrier; Robert D Timmerman
Journal:  J Oncol Pract       Date:  2012-05       Impact factor: 3.840

8.  Real-World Treatment Patterns in Patients with Castrate-Resistant Prostate Cancer and Bone Metastases.

Authors:  Lonnie Wen; Adriana Valderrama; Mary E Costantino; Stacey Simmons
Journal:  Am Health Drug Benefits       Date:  2019-05

9.  Authentication of Algorithm to Detect Metastases in Men with Prostate Cancer Using ICD-9 Codes.

Authors:  Matthew T Dolan; Sung Kim; Yu-Hsuan Shao; Grace L Lu-Yao
Journal:  Epidemiol Res Int       Date:  2012

10.  Cost-effectiveness analysis of treatments for metastatic castration resistant prostate cancer.

Authors:  Matthew E Pollard; Alan J Moskowitz; Michael A Diefenbach; Simon J Hall
Journal:  Asian J Urol       Date:  2016-12-13
  10 in total

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