| Literature DB >> 12495710 |
F Borrelli1, P Maffia, L Pinto, A Ianaro, A Russo, F Capasso, A Ialenti.
Abstract
Two ethanolic propolis extracts (EPE) with and without the caffeic acid phenethyl ester (CAPE), CAPE and galangin (major components of propolis) were investigated for anti-inflammatory activity in rats using carrageenin foot oedema, carrageenin pleurisy and adjuvant arthritis. In our experiments, EPE with CAPE and CAPE alone significantly inhibited carrageenin oedema, carrageenin pleurisy and adjuvant arthritis. In contrast EPE without CAPE and galangin did not exhibit anti-inflammatory effects in acute and chronic inflammation. These results suggest that the anti-inflammatory activity of propolis is due to CAPE.Entities:
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Year: 2002 PMID： 12495710 DOI： 10.1016/s0367-326x(02)00191-0
Source DB: PubMed Journal: Fitoterapia ISSN： 0367-326X Impact factor: 2.882