Literature DB >> 124948

HL-A LD (lymphocyte defined) typing: a rapid assay with primed lymphocytes.

M J Sheehy, P M Sondel, M L Bach, R Wank, F H Bach.   

Abstract

When human lymphocytes are cultured for 9 to 14 days with stimulating cells of a family member differing by a single HL-A haplotype they become "primed" to recognize specific HL-A LD (mixed lymphocyte culture) antigens. These primed lymphocytes respond specifically and rapidly when "restimulated" with cells of a person that contain the same LD antigens as those of the priming haplotype. Specific HL-A LD antigens can be detected within 24 hours by this primed LD typing.

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Year:  1975        PMID： 124948     DOI： 10.1126/science.124948

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  31 in total

1.  Heterogeneity of HLA defined in PLT: a cellular assay detects differences not seen using HLA-DRw serology.

Authors:  K S Zier; B Gänsbacher; S Scholz; E D Albert
Journal:  Immunogenetics       Date:  1980       Impact factor: 2.846

2.  Retention of specific proliferative capacity of cloned human T cells alloactivated against HLA-D alleles.

Authors:  G Pawelec; A Rehbein; B J Alter; P Wernet
Journal:  Immunogenetics       Date:  1980       Impact factor: 2.846

3.  Restimulation properties of human alloreactive cloned T-cell lines. Dissection of HLA-D-region alleles in population studies and in family segregation analysis.

Authors:  G Pawelec; P Wernet
Journal:  Immunogenetics       Date:  1980       Impact factor: 2.846

4.  Adherence of alloreactive lymphocytes to human arterial endothelial cell monolayers.

Authors:  Y L Colson; B H Markus; A Zeevi; R J Duquesnoy
Journal:  Clin Exp Immunol       Date:  1989-08       Impact factor: 4.330

5.  Association of PLT specificity of alloreactive lymphocyte clones with HLA-DR, MB and MT determinants.

Authors:  A Zeevi; C Scheffel; K Annen; G Bass; M Marrari; R J Duquesnoy
Journal:  Immunogenetics       Date:  1982       Impact factor: 2.846

6.  Characterization of human T-lymphocyte clones (TLCs) specific for HLA-region gene products.

Authors:  D D Eckels; R J Hartzman
Journal:  Immunogenetics       Date:  1982       Impact factor: 2.846

7.  Primed lymphocyte testing specificity of alloreactive lymphocyte clones for HLA-B locus determinants.

Authors:  A Zeevi; C Scheffel; K Annen; R J Duquesnoy
Journal:  Proc Natl Acad Sci U S A       Date:  1983-03       Impact factor: 11.205

8.  Analysis of the HLA-DRw8 haplotype: recognition by HTC typing of three distinct antigen complexes in Caucasians, Native Americans, and Orientals.

Authors:  E M Mickelson; B Nisperos; Z Layrisse; S J Kim; E D Thomas; J A Hansen
Journal:  Immunogenetics       Date:  1983       Impact factor: 2.846

9.  Defective autologous and allogeneic mixed lymphocyte reactions in hairy cell leukaemia.

Authors:  R A Knight; C P Worman; J C Cawley
Journal:  Clin Exp Immunol       Date:  1983-09       Impact factor: 4.330

10.  The bovine major histocompatibility complex (BoLa): close linkage of the genes controlling serologically defined antigens and mixed lymphocyte reactivity.

Authors:  W R Usinger; M Curie-Cohen; K Benforado; D Pringnitz; R Rowe; G A Splitter; W H Stone
Journal:  Immunogenetics       Date:  1981       Impact factor: 2.846
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