Literature DB >> 12491416

Natural products are biologically validated starting points in structural space for compound library development: solid-phase synthesis of dysidiolide-derived phosphatase inhibitors.

Dirk Brohm1, Susanne Metzger, Ajay Bhargava, Oliver Müller, Folker Lieb, Herbert Waldmann.   

Abstract

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Year:  2002        PMID: 12491416     DOI: 10.1002/1521-3773(20020118)41:2<307::aid-anie307>3.0.co;2-1

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN: 1433-7851            Impact factor:   15.336


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  8 in total

1.  Compound library development guided by protein structure similarity clustering and natural product structure.

Authors:  Marcus A Koch; Lars-Oliver Wittenberg; Sudipta Basu; Duraiswamy A Jeyaraj; Eleni Gourzoulidou; Kerstin Reinecke; Alex Odermatt; Herbert Waldmann
Journal:  Proc Natl Acad Sci U S A       Date:  2004-11-17       Impact factor: 11.205

Review 2.  Small molecule tools for functional interrogation of protein tyrosine phosphatases.

Authors:  Rongjun He; Li-Fan Zeng; Yantao He; Sheng Zhang; Zhong-Yin Zhang
Journal:  FEBS J       Date:  2012-08-16       Impact factor: 5.542

Review 3.  A Comprehensive Overview of the Developments of Cdc25 Phosphatase Inhibitors.

Authors:  Ahmed Bakr Abdelwahab; Eslam Reda El-Sawy; Atef G Hanna; Denyse Bagrel; Gilbert Kirsch
Journal:  Molecules       Date:  2022-04-07       Impact factor: 4.927

Review 4.  Natural products: a continuing source of novel drug leads.

Authors:  Gordon M Cragg; David J Newman
Journal:  Biochim Biophys Acta       Date:  2013-02-18

5.  Synthesis and Evaluation of a 2,11-Cembranoid-Inspired Library.

Authors:  Amanda J Welford; John J Caldwell; Manjuan Liu; Meirion Richards; Nathan Brown; Cara Lomas; Graham J Tizzard; Mateusz B Pitak; Simon J Coles; Suzanne A Eccles; Florence I Raynaud; Ian Collins
Journal:  Chemistry       Date:  2016-03-01       Impact factor: 5.236

6.  Synthesis of Bioconjugate Sesterterpenoids with Phospholipids and Polyunsaturated Fatty Acids.

Authors:  Ana Gil-Mesón; Alejandro M Roncero; Ignacio E Tobal; Pilar Basabe; David Díez; Faustino Mollinedo; Isidro S Marcos
Journal:  Molecules       Date:  2015-12-30       Impact factor: 4.411

Review 7.  The Methylene-Cycloalkylacetate (MCA) Scaffold in Terpenyl Compounds with Potential Pharmacological Activities.

Authors:  Ignacio E Tobal; Alejandro M Roncero; Rosalina F Moro; David Díez; Isidro S Marcos
Journal:  Molecules       Date:  2019-06-05       Impact factor: 4.411

8.  Exploring and mapping chemical space with molecular assembly trees.

Authors:  Yu Liu; Cole Mathis; Michał Dariusz Bajczyk; Stuart M Marshall; Liam Wilbraham; Leroy Cronin
Journal:  Sci Adv       Date:  2021-09-24       Impact factor: 14.136

  8 in total

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