Literature DB >> 12491222

Borderline tuberculoid leprosy: an immune reconstitution phenomenon in a human immunodeficiency virus-infected person.

S D Lawn1, C Wood, D N Lockwood.   

Abstract

Two months after starting highly active antiretroviral treatment (HAART), an individual with human immunodeficiency virus type 1 (HIV-1) infection and profound CD4+ T lymphocytopenia developed several erythematous plaques on his face, which were due to borderline tuberculoid leprosy with reversal reaction. The temporal association between the development of these lesions and changes in blood CD4+ lymphocyte count and plasma HIV-1 load observed during HAART strongly suggests that the presentation of leprosy resulted from immune reconstitution.

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Year:  2002        PMID: 12491222     DOI: 10.1086/344446

Source DB:  PubMed          Journal:  Clin Infect Dis        ISSN: 1058-4838            Impact factor:   9.079


  18 in total

1.  Leprosy after starting antiretroviral treatment.

Authors:  Stephen D Lawn; Diana N J Lockwood
Journal:  BMJ       Date:  2007-02-03

2.  Two patients coinfected with Mycobacterium leprae and human immunodeficiency virus type 1 and naive for antiretroviral therapy who exhibited type 1 leprosy reactions mimicking the immune reconstitution inflammatory syndrome.

Authors:  M A B Trindade; N Y S Valente; M I P Manini; M D F Takahashi; C F D Anjos; G Benard; B Naafs
Journal:  J Clin Microbiol       Date:  2006-10-04       Impact factor: 5.948

Review 3.  Immune restoration inflammatory syndromes: apparently paradoxical clinical events after the initiation of HAART.

Authors:  Matthias Stoll; Reinhold E Schmidt
Journal:  Curr HIV/AIDS Rep       Date:  2004-09       Impact factor: 5.071

4.  Lepromatous leprosy with erythema nodosum leprosum as immune reconstitution inflammatory syndrome in an HIV-1 infected patient after initiation of antiretroviral therapy.

Authors:  Alexia Cusini; Huldrych F Günthard; Rainer Weber; Milo Huber; Jivko Kamarashev; Barbara Bertisch; Silke Peter; Bernhard Beck
Journal:  BMJ Case Rep       Date:  2009-12-01

5.  HIV-M. leprae interaction: can HAART modify the course of leprosy?

Authors:  Euzenir Nunes Sarno; Ximena Illarramendi; José A Costa Nery; Anna M Sales; Maria C Gutierrez-Galhardo; Maria L Fernandes Penna; Elizabeth Pereira Sampaio; Gilla Kaplan
Journal:  Public Health Rep       Date:  2008 Mar-Apr       Impact factor: 2.792

6.  Human immunodeficiency virus and leprosy coinfection in Pune, India.

Authors:  Kulkarni Vinay; Joshi Smita; Gupte Nikhil; Gokhale Neeta
Journal:  J Clin Microbiol       Date:  2009-07-22       Impact factor: 5.948

Review 7.  [Immune restoration inflammatory syndromes].

Authors:  M Stoll; H Heiken; G M N Behrens; R E Schmidt
Journal:  Internist (Berl)       Date:  2004-08       Impact factor: 0.743

8.  Role of CD8(+) T cells in triggering reversal reaction in HIV/leprosy patients.

Authors:  Ariane Leite de Oliveira; Thaís Porto Amadeu; Andressa Cristina de França Gomes; Vinícius Martins Menezes; José Augusto da Costa Nery; Roberta Olmo Pinheiro; Euzenir Nunes Sarno
Journal:  Immunology       Date:  2013-09       Impact factor: 7.397

9.  Variations in leprosy manifestations among HIV-positive patients, Manaus, Brazil.

Authors:  Carolina Talhari; Christiane Matsuo; Anette Chrusciak-Talhari; Luis Carlos de-Lima-Ferreira; Marcelo Mira; Sinésio Talhari
Journal:  Emerg Infect Dis       Date:  2009-04       Impact factor: 6.883

10.  Leprosy as immune reconstitution inflammatory syndrome in HIV-positive persons.

Authors:  Frank Martiniuk; Shaline D Rao; Thomas H Rea; Michael S Glickman; Jerome Giovinazzo; William N Rom; Aloys Cabrera; William R Levis
Journal:  Emerg Infect Dis       Date:  2007-09       Impact factor: 6.883

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