| Literature DB >> 12490887 |
Torben Heick Jensen, Michael Rosbash.
Abstract
In eukaryotes, newly manufactured mRNA is subject to strict quality control. If certain standards are not met, offending messages are retained in the nucleus and degraded by the exosome complex. New data suggest that exosome-mediated processes are intimately coupled to the transcription machinery, which makes the mRNA in the first place.Mesh：
Substances：
Year: 2003 PMID： 12490887 DOI： 10.1038/nsb0103-10
Source DB: PubMed Journal: Nat Struct Biol ISSN： 1072-8368