| Literature DB >> 12489968 |
Frederik Menges1, Markus Neuburger, Andreas Pfaltz.
Abstract
[reaction: see text] A series of chiral phosphino-imidazolines (PHIM ligands) 1a-j with different substituents at the stereogenic center, the nitrogen atom of the imidazoline ring, and at the phosphorus atom were synthesized. Iridium complexes derived from these ligands have been evaluated as catalysts for the enantioselective hydrogenation of unfunctionalized olefins. In several cases, higher enantiomeric excesses were observed than with analogous phosphino-oxazoline ligands.Entities:
Year: 2002 PMID： 12489968 DOI： 10.1021/ol027253c
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005