Literature DB >> 12489685

Reactant- and product-based approaches to the design of combinatorial libraries.

Valerie J Gillet1.   

Abstract

Mesh:

Year:  2002        PMID: 12489685     DOI: 10.1023/a:1020825416871

Source DB:  PubMed          Journal:  J Comput Aided Mol Des        ISSN: 0920-654X            Impact factor:   3.686


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  24 in total

1.  Enhancing the hit-to-lead properties of lead optimization libraries

Authors: 
Journal:  J Chem Inf Comput Sci       Date:  2000-03

2.  Beyond mere diversity: tailoring combinatorial libraries for drug discovery.

Authors:  E J Martin; R E Critchlow
Journal:  J Comb Chem       Date:  1999-01

3.  Diversity screening versus focussed screening in drug discovery.

Authors: 
Journal:  Drug Discov Today       Date:  2000-07       Impact factor: 7.851

4.  Implementation of a system for reagent selection and library enumeration, profiling, and design.

Authors:  A R Leach; J Bradshaw; D V Green; M M Hann; J J Delany
Journal:  J Chem Inf Comput Sci       Date:  1999 Nov-Dec

5.  The in silico world of virtual libraries.

Authors: 
Journal:  Drug Discov Today       Date:  2000-08       Impact factor: 7.851

6.  A scoring scheme for discriminating between drugs and nondrugs.

Authors:  J Sadowski; H Kubinyi
Journal:  J Med Chem       Date:  1998-08-27       Impact factor: 7.446

7.  Can we learn to distinguish between "drug-like" and "nondrug-like" molecules?

Authors:  A Ajay; W P Walters; M A Murcko
Journal:  J Med Chem       Date:  1998-08-27       Impact factor: 7.446

8.  Identification of biological activity profiles using substructural analysis and genetic algorithms.

Authors:  V J Gillet; P Willett; J Bradshaw
Journal:  J Chem Inf Comput Sci       Date:  1998 Mar-Apr

9.  Rational combinatorial library design. 2. Rational design of targeted combinatorial peptide libraries using chemical similarity probe and the inverse QSAR approaches.

Authors:  S J Cho; W Zheng; A Tropsha
Journal:  J Chem Inf Comput Sci       Date:  1998 Mar-Apr

10.  Optimization and visualization of molecular diversity of combinatorial libraries.

Authors:  M Hassan; J P Bielawski; J C Hempel; M Waldman
Journal:  Mol Divers       Date:  1996-10       Impact factor: 2.943

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