Literature DB >> 124872

The anti-inflammatory actions of tilorone hydrochloride.

H Megel, A Raychaudhuri, I Shemano, T H Beaver, L L Thomas.   

Abstract

Tilorone suppressed inflammation induced by immune (direct passive Arthus reaction) as well as by non-immune agents (carrageenam-induced paw edema and abscess formation), if the compound is given 24 hr prior to the proinflammatory agonists. The non-immune anti-inflammatory effect is independent of the adrenals. A surprising findings was that total serum hemolytic complement is markedly elevated 24 hr after a single dose of tilorone.

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Year:  1975        PMID: 124872     DOI: 10.3181/00379727-149-38749

Source DB:  PubMed          Journal:  Proc Soc Exp Biol Med        ISSN: 0037-9727


  7 in total

1.  Effect of calcitonin on different inflammatory models.

Authors:  S E Abdullahi; E A Martelli; E Bramm; L Franco; G P Velo
Journal:  Agents Actions       Date:  1977-12

2.  [The regulation of acute inflammatory processes by systemic changes of plasma protein profiles].

Authors:  R Scherer; G Ruhenstroth-Bauer
Journal:  Naturwissenschaften       Date:  1977-09

3.  Dissociation between antiinflammatory action of tilorone and its interferon inducing activity.

Authors:  Y Hiyama; K Kuriyama
Journal:  Agents Actions       Date:  1991-07

4.  Renal lesions induced induced by tilorone and an analog. Ultrastructure and acid phosphatase study.

Authors:  W L Thelmo; S Levine
Journal:  Am J Pathol       Date:  1978-05       Impact factor: 4.307

5.  The Arthus reaction in rats, a possible test for anti-inflammatory and antiheumatic drugs.

Authors:  L R Pflum; M L Graeme
Journal:  Agents Actions       Date:  1979-06

6.  2,6-Di-tert-butyl-4-(2'-thenoyl)phenol(R-830): a novel nonsteroidal anti-inflammatory agent with antioxidant properties.

Authors:  G G Moore; K F Swingle
Journal:  Agents Actions       Date:  1982-12

7.  The immunopharmacologic and anti-inflammatory properties of RMI 9563 with special reference to its effect on the complement system.

Authors:  H Megel; A Raychaudhuri; M Bayer; T H Beaver
Journal:  Agents Actions       Date:  1978-04
  7 in total

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