Literature DB >> 12483716

Management of glucocorticoid-induced osteoporosis in patients with rheumatoid arthritis: rates and predictors of care in an academic rheumatology practice.

Daniel H Solomon1, Jeffrey N Katz, Jonathan P Jacobs, Alison M La Tourette, Jonathan Coblyn.   

Abstract

OBJECTIVE: To examine rheumatologists' management practices for patients with rheumatoid arthritis (RA) taking glucocorticoids seen at one academic medical rheumatology practice.
METHODS: All patients diagnosed with RA making at least 2 visits to the practice who were noted to be taking glucocorticoids on an index visit in January or February 1999 were included in a retrospective chart review.
RESULTS: Of the 623 eligible patients identified with RA, 236 patients were taking glucocorticoids at their index visit and were included in this study. The mean daily dosage of prednisone (or its equivalent) was 8.8 mg and the mean duration of use during the 2-year chart review was 15.4 months. Twenty-three percent of the study population underwent bone densitometry, and 42% were prescribed a medication that reduces bone loss (not including calcium and/or vitamin D). Calcium and/or vitamin D were noted on the medication lists of 25% of patients. Factors associated with not undergoing bone densitometry in adjusted logistic models included male patient sex and premenopausal status in women. No physician factors were significantly related to performing bone densitometry. Variables associated with not receiving prescription treatment of osteoporosis were male patient sex, premenopausal status, and having at least 1 comorbid condition.
CONCLUSION: Patients with RA taking oral glucocorticoids did not routinely undergo bone densitometry and/or receive prescription medications for osteoporosis. Men and premenopausal women were less likely to undergo bone densitometry and to receive a prescription medication for osteoporosis than postmenopausal women. Interventions to improve detection and prevention of glucocorticoid-induced osteoporosis are necessary.

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Year:  2002        PMID: 12483716     DOI: 10.1002/art.10613

Source DB:  PubMed          Journal:  Arthritis Rheum        ISSN: 0004-3591


  38 in total

1.  Trends and Determinants of Osteoporosis Treatment and Screening in Patients With Rheumatoid Arthritis Compared to Osteoarthritis.

Authors:  Gulsen Ozen; Diane L Kamen; Ted R Mikuls; Bryant R England; Frederick Wolfe; Kaleb Michaud
Journal:  Arthritis Care Res (Hoboken)       Date:  2018-03-11       Impact factor: 4.794

2.  Current management of corticosteroid-induced osteoporosis: variations in awareness and management.

Authors:  J G Ryan; R K Morgan; P J Lavin; F E Murray; P G O'Connell
Journal:  Ir J Med Sci       Date:  2004 Jan-Mar       Impact factor: 1.568

Review 3.  Glucocorticoid-induced osteoporosis: treatment options and guidelines.

Authors:  Michael Maricic
Journal:  Curr Osteoporos Rep       Date:  2005-03       Impact factor: 5.096

Review 4.  [Glucocorticoid induced osteoporosis].

Authors:  U Lange; U Müller-Ladner
Journal:  Z Rheumatol       Date:  2007-03       Impact factor: 1.372

5.  Osteoporosis in psoriatic arthritis: an assessment of densitometry and fragility fractures.

Authors:  Manuel Riesco; Francisco Manzano; Pilar Font; Alicia García; Joan M Nolla
Journal:  Clin Rheumatol       Date:  2013-07-12       Impact factor: 2.980

6.  An observational study of glucocorticoid-induced osteoporosis prophylaxis in a national cohort of male veterans with rheumatoid arthritis.

Authors:  L Caplan; A E Hines; E Williams; A V Prochazka; K G Saag; F Cunningham; E Hutt
Journal:  Osteoporos Int       Date:  2010-04-01       Impact factor: 4.507

Review 7.  Bone involvement in exogenous hypercortisolism.

Authors:  L Sinigaglia; D Mazzocchi; M Varenna
Journal:  J Endocrinol Invest       Date:  2008-04       Impact factor: 4.256

8.  Patterns of preventive health services in rheumatoid arthritis patients compared to a primary care patient population.

Authors:  Androniki Bili; Lisa L Schroeder; Lindsay J Ledwich; H Lester Kirchner; Eric D Newman; Mary Chester M Wasko
Journal:  Rheumatol Int       Date:  2010-03-27       Impact factor: 2.631

9.  Adherence to monthly and weekly oral bisphosphonates in women with osteoporosis.

Authors:  F-E Cotté; P Fardellone; F Mercier; A-F Gaudin; C Roux
Journal:  Osteoporos Int       Date:  2009-05-21       Impact factor: 4.507

10.  Factors associated with diagnosis and treatment of osteoporosis in older adults.

Authors:  S Nayak; M S Roberts; S L Greenspan
Journal:  Osteoporos Int       Date:  2009-01-17       Impact factor: 4.507

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