Literature DB >> 12482520

Antibody discovery: phage display.

Titus Kretzschmar1, Thomas von Rüden.   

Abstract

Phage display has proven to be a robust and convenient technology for the selection of high-quality human antibodies from diverse libraries. Besides enabling the identification of antibodies in a fast, high-throughput mode, which allows comprehensive protein expression analyses, phage display has been used to identify a fully human therapeutic antibody presently undergoing the regulatory process for market approval.

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Year:  2002        PMID： 12482520     DOI： 10.1016/s0958-1669(02)00380-4

Source DB:  PubMed          Journal:  Curr Opin Biotechnol        ISSN： 0958-1669            Impact factor:   9.740


  27 in total

Review 1.  Generation and production of engineered antibodies.

Authors:  Sergey M Kipriyanov; Fabrice Le Gall
Journal:  Mol Biotechnol       Date:  2004-01       Impact factor: 2.695

2.  Affinity enhancement of an in vivo matured therapeutic antibody using structure-based computational design.

Authors:  Louis A Clark; P Ann Boriack-Sjodin; John Eldredge; Christopher Fitch; Bethany Friedman; Karl J M Hanf; Matthew Jarpe; Stefano F Liparoto; You Li; Alexey Lugovskoy; Stephan Miller; Mia Rushe; Woody Sherman; Kenneth Simon; Herman Van Vlijmen
Journal:  Protein Sci       Date:  2006-04-05       Impact factor: 6.725

3.  Improved isolation of anti-rhTNF-alpha scFvs from phage display library by bioinformatics.

Authors:  Wei Chen; Juan Zhang; Tao Zhang; Haixin Li; Wenyi Wang; Zhinan Xia; Min Wang
Journal:  Mol Biotechnol       Date:  2009-05-02       Impact factor: 2.695

Review 4.  Glioblastoma cancer stem cells: Biomarker and therapeutic advances.

Authors:  Kelli B Pointer; Paul A Clark; Michael Zorniak; Bahauddeen M Alrfaei; John S Kuo
Journal:  Neurochem Int       Date:  2014-03-19       Impact factor: 3.921

Review 5.  Bacteriophage vehicles for phage display: biology, mechanism, and application.

Authors:  Walead Ebrahimizadeh; Masoumeh Rajabibazl
Journal:  Curr Microbiol       Date:  2014-03-18       Impact factor: 2.188

Review 6.  Integrating high-throughput screening and sequencing for monoclonal antibody discovery and engineering.

Authors:  Cristina Parola; Daniel Neumeier; Sai T Reddy
Journal:  Immunology       Date:  2017-10-30       Impact factor: 7.397

7.  Isolation and characterization of selective and potent human Fab inhibitors directed to the active-site region of the two-component NS2B-NS3 proteinase of West Nile virus.

Authors:  Sergey A Shiryaev; Ilian A Radichev; Boris I Ratnikov; Alexander E Aleshin; Katarzyna Gawlik; Boguslaw Stec; Christian Frisch; Achim Knappik; Alex Y Strongin
Journal:  Biochem J       Date:  2010-04-14       Impact factor: 3.857

8.  Clonal diversification in OspA-specific antibodies from peripheral circulation of a chronic Lyme arthritis patient.

Authors:  Srimoyee Ghosh; Brigitte T Huber
Journal:  J Immunol Methods       Date:  2007-02-06       Impact factor: 2.303

9.  Crystallization and molecular-replacement solution of a diagnostic fluorescent dye in complex with a specific Fab fragment.

Authors:  Roman C Hillig; Siegfried Baesler; Stefanie Urlinger; Yvonne Stark; Susanne Bauer; Volker Badock; Martina Huber; Inke Bahr; Michael Schirner; Kai Licha
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2007-02-23

10.  Affinity maturation by targeted diversification of the CDR-H2 loop of a monoclonal Fab derived from a synthetic naïve human antibody library and directed against the internal trimeric coiled-coil of gp41 yields a set of Fabs with improved HIV-1 neutralization potency and breadth.

Authors:  Elena Gustchina; John M Louis; Christian Frisch; Francisco Ylera; Annette Lechner; Carole A Bewley; G Marius Clore
Journal:  Virology       Date:  2009-08-19       Impact factor: 3.616
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