Literature DB >> 12482511

The use of substrate engineering in biohydroxylation.

Anna de Raadt1, Herfried Griengl.   

Abstract

In the biohydroxylation of nonactivated carbon atoms, substrate engineering has been found to be a very useful and simple means to influence substrate acceptance and the regioselectivity and stereoselectivity of this transformation. Recently, this methodology has been applied to the hydroxylation of a large number of compounds including cycloalkane carboxylic acids, ketones, amines, amides and alcohols.

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Year:  2002        PMID: 12482511     DOI: 10.1016/s0958-1669(02)00358-0

Source DB:  PubMed          Journal:  Curr Opin Biotechnol        ISSN: 0958-1669            Impact factor:   9.740


  3 in total

1.  Selective oxidation of carbolide C-H bonds by an engineered macrolide P450 mono-oxygenase.

Authors:  Shengying Li; Mani Raj Chaulagain; Allison R Knauff; Larissa M Podust; John Montgomery; David H Sherman
Journal:  Proc Natl Acad Sci U S A       Date:  2009-10-15       Impact factor: 11.205

Review 2.  Biocatalytic Oxidation Reactions: A Chemist's Perspective.

Authors:  JiaJia Dong; Elena Fernández-Fueyo; Frank Hollmann; Caroline E Paul; Milja Pesic; Sandy Schmidt; Yonghua Wang; Sabry Younes; Wuyuan Zhang
Journal:  Angew Chem Int Ed Engl       Date:  2018-07-03       Impact factor: 15.336

3.  Engineering enzyme catalysis: an inverse approach.

Authors:  Clare F Megarity
Journal:  Biosci Rep       Date:  2019-02-12       Impact factor: 3.840

  3 in total

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