Literature DB >> 12477885

Evidence for packaging of rep-cap sequences into adeno-associated virus (AAV) type 2 capsids in the absence of inverted terminal repeats: a model for generation of rep-positive AAV particles.

Pascale Nony1, Gilliane Chadeuf, Jacques Tessier, Philippe Moullier, Anna Salvetti.   

Abstract

We previously reported that a 350-bp region of the adeno-associated virus (AAV) type 2 rep gene contains a cis-acting element responsible for the Rep-dependent replication of a transiently transfected rep-cap plasmid. In this study, we further report that replicated rep-cap sequences can be packaged into AAV capsids in the absence of the inverted terminal repeats.

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Year:  2003        PMID： 12477885      PMCID： PMC140600          DOI： 10.1128/jvi.77.1.776-781.2003

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  16 in total

1.  Recombinant adeno-associated virus purification using novel methods improves infectious titer and yield.

Authors:  S Zolotukhin; B J Byrne; E Mason; I Zolotukhin; M Potter; K Chesnut; C Summerford; R J Samulski; N Muzyczka
Journal:  Gene Ther       Date:  1999-06       Impact factor: 5.250

2.  Efficient replication of adeno-associated virus type 2 vectors: a cis-acting element outside of the terminal repeats and a minimal size.

Authors:  G E Tullis; T Shenk
Journal:  J Virol       Date:  2000-12       Impact factor: 5.103

3.  DNA helicase-mediated packaging of adeno-associated virus type 2 genomes into preformed capsids.

Authors:  J A King; R Dubielzig; D Grimm; J A Kleinschmidt
Journal:  EMBO J       Date:  2001-06-15       Impact factor: 11.598

4.  Novel cis-acting replication element in the adeno-associated virus type 2 genome is involved in amplification of integrated rep-cap sequences.

Authors:  P Nony; J Tessier; G Chadeuf; P Ward; A Giraud; M Dugast; R M Linden; P Moullier; A Salvetti
Journal:  J Virol       Date:  2001-10       Impact factor: 5.103

5.  Chromosomal effects of adeno-associated virus vector integration.

Authors:  Daniel G Miller; Elizabeth A Rutledge; David W Russell
Journal:  Nat Genet       Date:  2002-01-22       Impact factor: 38.330

6.  In vitro resolution of covalently joined AAV chromosome ends.

Authors:  R O Snyder; R J Samulski; N Muzyczka
Journal:  Cell       Date:  1990-01-12       Impact factor: 41.582

7.  A novel terminal resolution-like site in the adeno-associated virus type 2 genome.

Authors:  X S Wang; A Srivastava
Journal:  J Virol       Date:  1997-02       Impact factor: 5.103

8.  Identification and elimination of replication-competent adeno-associated virus (AAV) that can arise by nonhomologous recombination during AAV vector production.

Authors:  J M Allen; D J Debelak; T C Reynolds; A D Miller
Journal:  J Virol       Date:  1997-09       Impact factor: 5.103

9.  Adeno-associated virus type 2 protein interactions: formation of pre-encapsidation complexes.

Authors:  R Dubielzig; J A King; S Weger; A Kern; J A Kleinschmidt
Journal:  J Virol       Date:  1999-11       Impact factor: 5.103

10.  Identification of linear DNA sequences that specifically bind the adeno-associated virus Rep protein.

Authors:  D M McCarty; D J Pereira; I Zolotukhin; X Zhou; J H Ryan; N Muzyczka
Journal:  J Virol       Date:  1994-08       Impact factor: 5.103
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  22 in total

Review 1.  Viral vectors for in vivo gene transfer in Parkinson's disease: properties and clinical grade production.

Authors:  Ronald J Mandel; Corinna Burger; Richard O Snyder
Journal:  Exp Neurol       Date:  2007-08-24       Impact factor: 5.330

2.  Undetectable transcription of cap in a clinical AAV vector: implications for preformed capsid in immune responses.

Authors:  Bernd Hauck; Samuel L Murphy; Peter H Smith; Guang Qu; Xingge Liu; Olga Zelenaia; Federico Mingozzi; Jürg M Sommer; Katherine A High; J Fraser Wright
Journal:  Mol Ther       Date:  2008-10-21       Impact factor: 11.454

3.  OneBac: platform for scalable and high-titer production of adeno-associated virus serotype 1-12 vectors for gene therapy.

Authors:  Mario Mietzsch; Sabrina Grasse; Catherine Zurawski; Stefan Weger; Antonette Bennett; Mavis Agbandje-McKenna; Nicholas Muzyczka; Sergei Zolotukhin; Regine Heilbronn
Journal:  Hum Gene Ther       Date:  2014-01-23       Impact factor: 5.695

4.  OneBac 2.0: Sf9 Cell Lines for Production of AAV5 Vectors with Enhanced Infectivity and Minimal Encapsidation of Foreign DNA.

Authors:  Mario Mietzsch; Vincent Casteleyn; Stefan Weger; Sergei Zolotukhin; Regine Heilbronn
Journal:  Hum Gene Ther       Date:  2015-08-06       Impact factor: 5.695

5.  Inverted terminal repeat sequences are important for intermolecular recombination and circularization of adeno-associated virus genomes.

Authors:  Ziying Yan; Roman Zak; Yulong Zhang; John F Engelhardt
Journal:  J Virol       Date:  2005-01       Impact factor: 5.103

6.  Adeno-Associated Virus Vector Mobilization, Risk Versus Reality.

Authors:  Liujiang Song; R Jude Samulski; Matthew L Hirsch
Journal:  Hum Gene Ther       Date:  2020-10       Impact factor: 5.695

7.  Nanopore sequencing of native adeno-associated virus (AAV) single-stranded DNA using a transposase-based rapid protocol.

Authors:  Marco T Radukic; David Brandt; Markus Haak; Kristian M Müller; Jörn Kalinowski
Journal:  NAR Genom Bioinform       Date:  2020-09-28

8.  Four-dimensional visualization of the simultaneous activity of alternative adeno-associated virus replication origins.

Authors:  Daniel L Glauser; Okay Saydam; N Alexander Balsiger; Irma Heid; R Michael Linden; Mathias Ackermann; Cornel Fraefel
Journal:  J Virol       Date:  2005-10       Impact factor: 5.103

9.  The cellular TATA binding protein is required for rep-dependent replication of a minimal adeno-associated virus type 2 p5 element.

Authors:  Achille François; Mickaël Guilbaud; Rafi Awedikian; Gilliane Chadeuf; Philippe Moullier; Anna Salvetti
Journal:  J Virol       Date:  2005-09       Impact factor: 5.103

10.  The Adeno-Associated Virus Genome Packaging Puzzle.

Authors:  Chen Ling; Yuan Wang; Yuan Lu; Lina Wang; Giridhara R Jayandharan; George V Aslanidi; Baozheng Li; Binbin Cheng; Wenqin Ma; Thomas Lentz; Changquan Ling; Xiao Xiao; R Jude Samulski; Nicholas Muzyczka; Arun Srivastava
Journal:  J Mol Genet Med       Date:  2015-07-15
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