Literature DB >> 12475780

Intracellular targeting of protein kinases and phosphatases.

Neal Alto1, Jennifer J Carlisle Michel, Kimberly L Dodge, Lorene K Langeberg, John D Scott.   

Abstract

Compartmentalization of kinases and phosphatases is a key determinant in the specificity of second messenger-mediated signaling events. Localization of the cAMP-dependent protein kinase (PKA) and other signaling enzymes is mediated by interaction with A-kinase anchoring proteins (AKAPs). This study focused on recent advances that further our understanding of AKAPs, with particular emphasis on the bidirectional regulation of signaling events by AKAP signaling complexes and their contribution to the control of actin reorganization events.

Mesh：

Substances：

Year:  2002        PMID： 12475780     DOI： 10.2337/diabetes.51.2007.s385

Source DB:  PubMed          Journal:  Diabetes        ISSN： 0012-1797            Impact factor:   9.461


  17 in total

Review 1.  The role of serine/threonine protein phosphatases in exocytosis.

Authors:  Alistair T R Sim; Monique L Baldwin; John A P Rostas; Jeff Holst; Russell I Ludowyke
Journal:  Biochem J       Date:  2003-08-01       Impact factor: 3.857

2.  The pleckstrin homology domain-containing protein CKIP-1 is involved in regulation of cell morphology and the actin cytoskeleton and interaction with actin capping protein.

Authors:  David A Canton; Mary Ellen K Olsten; Kyoungtae Kim; Amanda Doherty-Kirby; Gilles Lajoie; John A Cooper; David W Litchfield
Journal:  Mol Cell Biol       Date:  2005-05       Impact factor: 4.272

3.  The role of CKIP-1 in cell morphology depends on its interaction with actin-capping protein.

Authors:  David A Canton; Mary Ellen K Olsten; Hanspeter Niederstrasser; John A Cooper; David W Litchfield
Journal:  J Biol Chem       Date:  2006-09-20       Impact factor: 5.157

4.  Dynamically committed, uncommitted, and quenched states encoded in protein kinase A revealed by NMR spectroscopy.

Authors:  Larry R Masterson; Lei Shi; Emily Metcalfe; Jiali Gao; Susan S Taylor; Gianluigi Veglia
Journal:  Proc Natl Acad Sci U S A       Date:  2011-04-06       Impact factor: 11.205

Review 5.  Mechanisms of action of glucagon-like peptide 1 in the pancreas.

Authors:  Máire E Doyle; Josephine M Egan
Journal:  Pharmacol Ther       Date:  2006-12-28       Impact factor: 12.310

6.  Protein kinase A regulates AKAP250 (gravin) scaffold binding to the beta2-adrenergic receptor.

Authors:  Jiangchuan Tao; Hsien-Yu Wang; Craig C Malbon
Journal:  EMBO J       Date:  2003-12-15       Impact factor: 11.598

7.  A molecular switch for targeting between endoplasmic reticulum (ER) and mitochondria: conversion of a mitochondria-targeting element into an ER-targeting signal in DAKAP1.

Authors:  Yuliang Ma; Susan S Taylor
Journal:  J Biol Chem       Date:  2008-02-19       Impact factor: 5.157

8.  Src homology 2 domain-containing phosphatase 2 (Shp2) is a component of the A-kinase-anchoring protein (AKAP)-Lbc complex and is inhibited by protein kinase A (PKA) under pathological hypertrophic conditions in the heart.

Authors:  Brian T Burmeister; Domenico M Taglieri; Li Wang; Graeme K Carnegie
Journal:  J Biol Chem       Date:  2012-10-08       Impact factor: 5.157

9.  The PKARIalpha subunit of protein kinase A modulates the activation of p90RSK1 and its function.

Authors:  Deepti Chaturvedi; Michael S Cohen; Jack Taunton; Tarun B Patel
Journal:  J Biol Chem       Date:  2009-07-01       Impact factor: 5.157

10.  Alpha-kinase anchoring protein alphaKAP interacts with SERCA2A to spatially position Ca2+/calmodulin-dependent protein kinase II and modulate phospholamban phosphorylation.

Authors:  Puneet Singh; Maysoon Salih; Balwant S Tuana
Journal:  J Biol Chem       Date:  2009-08-11       Impact factor: 5.157
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