Literature DB >> 1246620

Genetic characteristics of the HeLa cell.

S H Hsu, B Z Schacter, N L Delaney, T B Miller, V A McKusick, R H Kennett, J G Bodmer, D Young, W F Bodmer.   

Abstract

The genotype of the patient Henrietta Lacks from whose cervical carcinoma the HeLa cell was derived was deduced from the phenotypes of her husband and children, and from studies of the HeLa cell. Hemizygous expression of glucose-6-phosphate dehydrogenase in HeLa, together with the deduced heterozygosity of Mrs. Lacks, is consistent with clonal origin of her neoplasm.

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Year:  1976        PMID： 1246620     DOI： 10.1126/science.1246620

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  16 in total

1.  A new DNA profiling system for cell line identification for use in cell banks in Japan.

Authors:  M Honma; E Kataoka; K Ohnishi; T Ohno; M Takeuchi; N Nomura; H Mizusawa
Journal:  In Vitro Cell Dev Biol       Date:  1992-01

2.  Application of DNA fingerprints for cell-line individualization.

Authors:  D A Gilbert; Y A Reid; M H Gail; D Pee; C White; R J Hay; S J O'Brien
Journal:  Am J Hum Genet       Date:  1990-09       Impact factor: 11.025

3.  Characterization of the WIDR: a human colon carcinoma cell line.

Authors:  P Noguchi; R Wallace; J Johnson; E M Earley; S O'Brien; S Ferrone; M A Pellegrino; J Milstien; C Needy; W Browne; J Petricciani
Journal:  In Vitro       Date:  1979-06

4.  Assignment of the chloramphenicol resistance gene to mitochondrial deoxyribonucleic acid and analysis of its expression in cultured human cells.

Authors:  D C Wallace
Journal:  Mol Cell Biol       Date:  1981-08       Impact factor: 4.272

5.  Demonstration of T-cell and K-cell cytotoxicity against measles-infected cells in normal subjects, multiple sclerosis and subacute sclerosing panencephalitis.

Authors:  P W Ewan; P J Lachmann
Journal:  Clin Exp Immunol       Date:  1977-10       Impact factor: 4.330

6.  Lack of complementation between xeroderma pigmentosum complementation groups D and H.

Authors:  R T Johnson; G C Elliott; S Squires; V C Joysey
Journal:  Hum Genet       Date:  1989-02       Impact factor: 4.132

7.  Tissue typing the HLA-A locus from genomic DNA by sequence-specific PCR: comparison of HLA genotype and surface expression on colorectal tumor cell lines.

Authors:  M J Browning; P Krausa; A Rowan; D C Bicknell; J G Bodmer; W F Bodmer
Journal:  Proc Natl Acad Sci U S A       Date:  1993-04-01       Impact factor: 11.205

8.  Histochemical evidence for sulfomucins at the surface of Hela cells.

Authors:  M Mareel; C Dragonetti; G De Bruyne
Journal:  Histochemistry       Date:  1976-10-29

9.  Highly lytic CD8+, alpha beta T-cell receptor cytotoxic T cells with major histocompatibility complex (MHC) class I antigen-directed cytotoxicity in beta 2-microglobulin, MHC class I-deficient mice.

Authors:  S Apasov; M Sitkovsky
Journal:  Proc Natl Acad Sci U S A       Date:  1993-04-01       Impact factor: 11.205

10.  A molecular approach to the identification and individualization of human and animal cells in culture: isozyme and allozyme genetic signatures.

Authors:  S J O'Brien; J E Shannon; M H Gail
Journal:  In Vitro       Date:  1980-02
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