OBJECTIVE: To compare the intraobserver reliability and the sensitivity to change of 2 techniques evaluating the cartilage breakdown in hip osteoarthritis (OA). DESIGN: 3 year longitudinal study. PARTICIPANTS: patients with painful hip OA. OUTCOME: coxofemoral joint space width (JSW) at baseline and at 3 year followup was measured on anteroposterior weight-bearing radiographs by 2 methods: a manual method to obtain JSW at the narrowest point (minimal JSW) using a 0.1 mm graduated magnifying glass and a computer based method to obtain minimal and average JSW. STATISTICAL ANALYSIS: Two assessments, at one month interval, of each pair of films; evaluation of the intraobserver reliability using the intraclass coefficient of correlation, and the Bland and Altman approach, obtaining the smallest detectable difference (SDD). For each technique, percentage of progressors was evaluated, i.e., the percentage of patients with change greater than the SDD. Evaluation of sensitivity to change was performed using the standardized response mean (SRM), with 95% CI calculated using the jackknife method. RESULTS: Twenty-five pairs of films were evaluated. There were no statistically significant differences between the 3 analyses in the calculated intraclass coefficients of correlation, percentage of progressors, or SRM. CONCLUSION: These results suggest that both techniques are reliable and sensitive enough to detect changes in a relevant percentage of patients with hip OA after a 3 year followup.
OBJECTIVE: To compare the intraobserver reliability and the sensitivity to change of 2 techniques evaluating the cartilage breakdown in hip osteoarthritis (OA). DESIGN: 3 year longitudinal study. PARTICIPANTS: patients with painful hip OA. OUTCOME: coxofemoral joint space width (JSW) at baseline and at 3 year followup was measured on anteroposterior weight-bearing radiographs by 2 methods: a manual method to obtain JSW at the narrowest point (minimal JSW) using a 0.1 mm graduated magnifying glass and a computer based method to obtain minimal and average JSW. STATISTICAL ANALYSIS: Two assessments, at one month interval, of each pair of films; evaluation of the intraobserver reliability using the intraclass coefficient of correlation, and the Bland and Altman approach, obtaining the smallest detectable difference (SDD). For each technique, percentage of progressors was evaluated, i.e., the percentage of patients with change greater than the SDD. Evaluation of sensitivity to change was performed using the standardized response mean (SRM), with 95% CI calculated using the jackknife method. RESULTS: Twenty-five pairs of films were evaluated. There were no statistically significant differences between the 3 analyses in the calculated intraclass coefficients of correlation, percentage of progressors, or SRM. CONCLUSION: These results suggest that both techniques are reliable and sensitive enough to detect changes in a relevant percentage of patients with hip OA after a 3 year followup.
Authors: P Ornetti; K Brandt; M-P Hellio-Le Graverand; M Hochberg; D J Hunter; M Kloppenburg; N Lane; J-F Maillefert; S A Mazzuca; T Spector; G Utard-Wlerick; E Vignon; M Dougados Journal: Osteoarthritis Cartilage Date: 2009-02-09 Impact factor: 6.576
Authors: D Chu Miow Lin; W M Reichmann; L Gossec; E Losina; P G Conaghan; J F Maillefert Journal: Osteoarthritis Cartilage Date: 2011-03-23 Impact factor: 6.576
Authors: Kasper Huétink; Ronald van 't Klooster; Bart L Kaptein; Iain Watt; Margreet Kloppenburg; Rob G H H Nelissen; Johan H C Reiber; Berend C Stoel Journal: Skeletal Radiol Date: 2011-02-11 Impact factor: 2.199
Authors: Emmanuel Maheu; Christian Cadet; Marc Marty; Maxime Dougados; Salah Ghabri; Isabelle Kerloch; Bernard Mazières; Tim D Spector; Eric Vignon; Michel G Lequesne Journal: Arthritis Res Ther Date: 2005-10-05 Impact factor: 5.156