OBJECTIVE: Cerebrospinal fluid rhinorrhea, pneumocephalus and meningitis are serious complications following transsphenoidal excision of sellar, suprasellar and parasellar lesions. This study evaluates the use of a new bioadhesive, Bioglue as an adjunct in reconstructing the sellar floor and preventing CSF fistula and investigates the possible complications associated with its use. METHODS: In thirty-two patients (31 pituitary adenomas and 1 meningioma) Bioglue was used to help reconstruct the sellar floor after endonasal transsphenoidal procedures between January 2001 and April 2002 at the Royal Melbourne Hospital. RESULTS: There were no post-operative CSF rhinorrhea, allergic rhinitis, meningitis, pneumocranium, granulomas or other complications associated with the use of Bioglue. CONCLUSION: This technique of reconstruction of sellar floor using Bioglue is simple and time efficient in preventing CSF fistula formation following transsphenoidal procedures for sellar region lesions.
OBJECTIVE: Cerebrospinal fluid rhinorrhea, pneumocephalus and meningitis are serious complications following transsphenoidal excision of sellar, suprasellar and parasellar lesions. This study evaluates the use of a new bioadhesive, Bioglue as an adjunct in reconstructing the sellar floor and preventing CSF fistula and investigates the possible complications associated with its use. METHODS: In thirty-two patients (31 pituitary adenomas and 1 meningioma) Bioglue was used to help reconstruct the sellar floor after endonasal transsphenoidal procedures between January 2001 and April 2002 at the Royal Melbourne Hospital. RESULTS: There were no post-operative CSF rhinorrhea, allergic rhinitis, meningitis, pneumocranium, granulomas or other complications associated with the use of Bioglue. CONCLUSION: This technique of reconstruction of sellar floor using Bioglue is simple and time efficient in preventing CSF fistula formation following transsphenoidal procedures for sellar region lesions.
Authors: James Shin; Jonathan Forbes; Kurt Lehner; Hilarie Tomasiewicz; Theodore H Schwartz; C Douglas Phillips Journal: J Neurol Surg B Skull Base Date: 2018-07-20
Authors: Brian J Dlouhy; Karthik Madhavan; John D Clinger; Ambur Reddy; Jeffrey D Dawson; Erin K O'Brien; Eugene Chang; Scott M Graham; Jeremy D W Greenlee Journal: J Neurosurg Date: 2012-03-23 Impact factor: 5.115
Authors: M O van Aken; R A Feelders; S de Marie; J H van de Berge; A H G Dallenga; E J Delwel; R M L Poublon; J A Romijn; A J van der Lely; S W J Lamberts; W W de Herder Journal: Pituitary Date: 2004 Impact factor: 4.107