| Literature DB >> 12462144 |
Celia W Goulding1, Marcin Apostol, Daniel H Anderson, Harindarpal S Gill, Clare V Smith, Mack R Kuo, Jin Kuk Yang, Geoffrey S Waldo, Se Won Suh, Radha Chauhan, Avinash Kale, Nandita Bachhawat, Shekhar C Mande, Jodie M Johnston, J Shaun Lott, Edward N Baker, Vickery L Arcus, David Leys, Kirsty J McLean, Andrew W Munro, Joel Berendzen, Vivek Sharma, Min S Park, David Eisenberg, James Sacchettini, Tom Alber, Bernhard Rupp, William Jacobs, Thomas C Terwilliger.
Abstract
Structural genomics, the large-scale determination of protein structures, promises to provide a broad structural foundation for drug discovery. The tuberculosis (TB) Structural Genomics Consortium is devoted to encouraging, coordinating, and facilitating the determination of structures of proteins from Mycobacterium tuberculosis and hopes to determine 400 TB protein structures over 5 years. The Consortium has determined structures of 28 proteins from TB to date. These protein structures are already providing a basis for drug discovery efforts.Entities:
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Year: 2002 PMID： 12462144 DOI： 10.2174/1568005023342551
Source DB: PubMed Journal: Curr Drug Targets Infect Disord ISSN： 1568-0053