Literature DB >> 12461519

Microbicides: a new approach to preventing HIV and other sexually transmitted infections.

Alan Stone1.   

Abstract

Many chemical agents can block human immunodeficiency virus (HIV) infection in the laboratory. Scientists are investigating which of these, used intravaginally by women, will safely prevent the sexual transmission of HIV in humans. Several such products - microbicides - will soon be tested in populations at high risk for HIV, and others are waiting in the wings. Microbicides will provide a low-cost method, controlled by women, for protection against HIV, other sexually transmitted pathogens and unwanted pregnancy, and will therefore have global public-health benefits.

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Year:  2002        PMID： 12461519     DOI： 10.1038/nrd959

Source DB:  PubMed          Journal:  Nat Rev Drug Discov        ISSN： 1474-1776            Impact factor:   84.694


  63 in total

1.  Submicron Matrices Embedded in a Polymeric Caplet for Extended Intravaginal Delivery of Zidovudine.

Authors:  Felix Mashingaidze; Yahya E Choonara; Pradeep Kumar; Lisa C du Toit; Vinesh Maharaj; Eckhart Buchmann; Viness Pillay
Journal:  AAPS J       Date:  2017-08-04       Impact factor: 4.009

2.  Enzymatic triggered release of an HIV-1 entry inhibitor from prostate specific antigen degradable microparticles.

Authors:  Meredith R Clark; Hyder A Aliyar; Chang-won Lee; Julie I Jay; Kavita M Gupta; Karen M Watson; Russell J Stewart; Robert W Buckheit; Patrick F Kiser
Journal:  Int J Pharm       Date:  2011-04-12       Impact factor: 5.875

3.  The effects of inhomogeneous boundary dilution on the coating flow of an anti-HIV microbicide vehicle.

Authors:  Savas Tasoglu; Jennifer J Peters; Su Chan Park; Stéphane Verguet; David F Katz; Andrew J Szeri
Journal:  Phys Fluids (1994)       Date:  2011-09-15       Impact factor: 3.521

4.  Development of a new methodology for screening of human immunodeficiency virus type 1 microbicides based on real-time PCR quantification.

Authors:  Renato S Aguiar; Luciana J Costa; Helena S Pereira; Rodrigo M Brindeiro; Amilcar Tanuri
Journal:  Antimicrob Agents Chemother       Date:  2006-11-20       Impact factor: 5.191

Review 5.  Effectiveness of female controlled barrier methods in preventing sexually transmitted infections and HIV: current evidence and future research directions.

Authors:  A M Minnis; N S Padian
Journal:  Sex Transm Infect       Date:  2005-06       Impact factor: 3.519

6.  Dynamics of HIV neutralization by a microbicide formulation layer: biophysical fundamentals and transport theory.

Authors:  Anthony R Geonnotti; David F Katz
Journal:  Biophys J       Date:  2006-06-30       Impact factor: 4.033

7.  Quantitative perceptual differences among over-the-counter vaginal products using a standardized methodology: implications for microbicide development.

Authors:  Ellen D Mahan; Kathleen M Morrow; John E Hayes
Journal:  Contraception       Date:  2011-01-07       Impact factor: 3.375

8.  Anal and dry sex in commercial sex work, and relation to risk for sexually transmitted infections and HIV in Meru, Kenya.

Authors:  M Schwandt; C Morris; A Ferguson; E Ngugi; S Moses
Journal:  Sex Transm Infect       Date:  2006-06-21       Impact factor: 3.519

9.  The microbicide tenofovir does not inhibit nucleic acid amplification tests for detection of Chlamydia trachomatis and Neisseria gonorrhoeae in urine samples.

Authors:  Billie Jo Wood; Patricia Rizzo-Price; Jeff Holden; Andrew Hardick; Thomas C Quinn; Charlotte A Gaydos
Journal:  J Clin Microbiol       Date:  2007-12-05       Impact factor: 5.948

Review 10.  Vaginal drug distribution modeling.

Authors:  David F Katz; Andrew Yuan; Yajing Gao
Journal:  Adv Drug Deliv Rev       Date:  2015-04-28       Impact factor: 15.470
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