Literature DB >> 12459347

Nutrigenomics: exploiting systems biology in the nutrition and health arena.

Ben van Ommen1, Rob Stierum.   

Abstract

Nutritional sciences are discovering the application of the so-called "omics" sciences. Propelled by the recent unravelling of the human genome and the coinciding technological developments, genotyping, transcriptomics, proteomics and metabolomics are now available to nutritional research. In the future we are likely to see new screening tools for the selection of bioactive nutrients, new biomarkers for the in vivo efficacy of nutrients, and better insight into the influence of genetic polymorphisms on nutrient metabolism. However, are these promises just based on biotechnological hype or is a real fundamental change in human nutritional sciences at hand?

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Year:  2002        PMID： 12459347     DOI： 10.1016/s0958-1669(02)00349-x

Source DB:  PubMed          Journal:  Curr Opin Biotechnol        ISSN： 0958-1669            Impact factor:   9.740


  28 in total

Review 1.  Genetic variation and lipid metabolism: modulation by dietary factors.

Authors:  Jose M Ordovas; Dolores Corella
Journal:  Curr Cardiol Rep       Date:  2005-11       Impact factor: 2.931

2.  Individual variation in macronutrient regulation measured by proton magnetic resonance spectroscopy of human plasma.

Authors:  Youngja Park; Seoung Bum Kim; Bing Wang; Roberto A Blanco; Ngoc-Anh Le; Shaoxiong Wu; Carolyn J Accardi; R Wayne Alexander; Thomas R Ziegler; Dean P Jones
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2009-05-20       Impact factor: 3.619

3.  Owner controlled data exchange in nutrigenomic collaborations: the NuGO information network.

Authors:  Ulrich Harttig; Anthony J Travis; Philippe Rocca-Serra; Marten Renkema; Ben van Ommen; Heiner Boeing
Journal:  Genes Nutr       Date:  2009-04-30       Impact factor: 5.523

4.  The challenges for molecular nutrition research 2: quantification of the nutritional phenotype.

Authors:  Ben van Ommen; Jaap Keijer; Robert Kleemann; Ruan Elliott; Christian A Drevon; Harry McArdle; Mike Gibney; Michael Müller
Journal:  Genes Nutr       Date:  2008-06-25       Impact factor: 5.523

Review 5.  Biochemical individuality reflected in chromatographic, electrophoretic and mass-spectrometric profiles.

Authors:  Milos V Novotny; Helena A Soini; Yehia Mechref
Journal:  J Chromatogr B Analyt Technol Biomed Life Sci       Date:  2008-04-15       Impact factor: 3.205

Review 6.  High-sensitivity analytical approaches for the structural characterization of glycoproteins.

Authors:  William R Alley; Benjamin F Mann; Milos V Novotny
Journal:  Chem Rev       Date:  2013-03-27       Impact factor: 60.622

7.  A sulfur amino acid-free meal increases plasma lipids in humans.

Authors:  Youngja Park; Ngoc-Anh Le; Tianwei Yu; Fred Strobel; Nana Gletsu-Miller; Carolyn J Accardi; Kichun S Lee; Shaoxiong Wu; Thomas R Ziegler; Dean P Jones
Journal:  J Nutr       Date:  2011-06-15       Impact factor: 4.798

Review 8.  Potential value of nutrigenomics in Crohn's disease.

Authors:  Lynnette R Ferguson
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2012-03-13       Impact factor: 46.802

9.  Genotype-phenotype associations: modulation by diet and obesity.

Authors:  Jose M Ordovas
Journal:  Obesity (Silver Spring)       Date:  2008-12       Impact factor: 5.002

10.  Mass-spectrometry-based metabolomics: limitations and recommendations for future progress with particular focus on nutrition research.

Authors:  Augustin Scalbert; Lorraine Brennan; Oliver Fiehn; Thomas Hankemeier; Bruce S Kristal; Ben van Ommen; Estelle Pujos-Guillot; Elwin Verheij; David Wishart; Suzan Wopereis
Journal:  Metabolomics       Date:  2009-06-12       Impact factor: 4.290
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