Literature DB >> 12450788

The EZH2 polycomb transcriptional repressor--a marker or mover of metastatic prostate cancer?

William R Sellers1, Massimo Loda.   

Abstract

The recent finding of overexpression of the polycomb group transcriptional repressor EZH2 in prostate cancer raises the possibility that transcriptional regulation at the chromatin level may play a role in the development of the metastatic phenotype and suggests new avenues of exploration with respect to patient stratification and therapeutics.

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Year:  2002        PMID： 12450788     DOI： 10.1016/s1535-6108(02)00187-3

Source DB:  PubMed          Journal:  Cancer Cell        ISSN： 1535-6108            Impact factor:   31.743


  39 in total

Review 1.  Identification of driver and passenger DNA methylation in cancer by epigenomic analysis.

Authors:  Satish Kalari; Gerd P Pfeifer
Journal:  Adv Genet       Date:  2010       Impact factor: 1.944

2.  Sustained JNK1 activation is associated with altered histone H3 methylations in human liver cancer.

Authors:  Qingshan Chang; Yadong Zhang; Kevin J Beezhold; Deepak Bhatia; Hongwen Zhao; Jianguo Chen; Vince Castranova; Xianglin Shi; Fei Chen
Journal:  J Hepatol       Date:  2008-10-16       Impact factor: 25.083

3.  Targeting monoamine oxidase A in advanced prostate cancer.

Authors:  Vincent Flamand; Hongjuan Zhao; Donna M Peehl
Journal:  J Cancer Res Clin Oncol       Date:  2010-03-04       Impact factor: 4.553

Review 4.  Histone demethylases and cancer.

Authors:  Sotirios C Kampranis; Philip N Tsichlis
Journal:  Adv Cancer Res       Date:  2009       Impact factor: 6.242

5.  Cell autonomous role of PTEN in regulating castration-resistant prostate cancer growth.

Authors:  David J Mulholland; Linh M Tran; Yunfeng Li; Houjian Cai; Ashkan Morim; Shunyou Wang; Seema Plaisier; Isla P Garraway; Jiaoti Huang; Thomas G Graeber; Hong Wu
Journal:  Cancer Cell       Date:  2011-05-27       Impact factor: 31.743

6.  Regulators of gene expression as biomarkers for prostate cancer.

Authors:  Stacey S Willard; Shahriar Koochekpour
Journal:  Am J Cancer Res       Date:  2012-11-20       Impact factor: 6.166

7.  MicroRNA-101 negatively regulates Ezh2 and its expression is modulated by androgen receptor and HIF-1alpha/HIF-1beta.

Authors:  Paul Cao; Zhiyong Deng; Meimei Wan; Weiwei Huang; Scott D Cramer; Jianfeng Xu; Ming Lei; Guangchao Sui
Journal:  Mol Cancer       Date:  2010-05-17       Impact factor: 27.401

8.  The polycomb group protein Bmi-1 represses the tumor suppressor PTEN and induces epithelial-mesenchymal transition in human nasopharyngeal epithelial cells.

Authors:  Li-Bing Song; Jun Li; Wen-Ting Liao; Yan Feng; Chun-Ping Yu; Li-Juan Hu; Qing-Li Kong; Li-Hua Xu; Xing Zhang; Wan-Li Liu; Man-Zhi Li; Ling Zhang; Tie-Bang Kang; Li-Wu Fu; Wen-Lin Huang; Yun-Fei Xia; Sai Wah Tsao; Mengfeng Li; Vimla Band; Hamid Band; Qing-Hua Shi; Yi-Xin Zeng; Mu-Sheng Zeng
Journal:  J Clin Invest       Date:  2009-11-02       Impact factor: 14.808

9.  Polycomb group-dependent Cyclin A repression in Drosophila.

Authors:  Anne-Marie Martinez; Sophie Colomb; Jérôme Déjardin; Frédéric Bantignies; Giacomo Cavalli
Journal:  Genes Dev       Date:  2006-02-15       Impact factor: 11.361

10.  Anti-oncogenic and pro-differentiation effects of clorgyline, a monoamine oxidase A inhibitor, on high grade prostate cancer cells.

Authors:  Hongjuan Zhao; Vincent Flamand; Donna M Peehl
Journal:  BMC Med Genomics       Date:  2009-08-20       Impact factor: 3.063
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