| Literature DB >> 12447981 |
Abstract
The folding of RNA sequences into secondary structures is a simple yet biophysically grounded model of a genotype-phenotype map. Its computational and mathematical analysis has uncovered a surprisingly rich statistical structure characterized by shape space covering, neutral networks and plastogenetic congruence. I review these concepts and discuss their evolutionary implications. Copyright 2002 Wiley-Periodicals, Inc.Entities:
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Year: 2002 PMID: 12447981 DOI: 10.1002/bies.10190
Source DB: PubMed Journal: Bioessays ISSN: 0265-9247 Impact factor: 4.345