Literature DB >> 12447586

Biodegradation of tungsten embolisation coils used in children.

Christoph Kampmann1, Rita Brzezinska, Moji Abidini, Anke Wenzel, Carl-Friedrich Wippermann, Pirmin Habermehl, Markus Knuf, Reinhard Schumacher.   

Abstract

BACKGROUND: It has been suggested that tungsten coils (TCs) may corrode 30 months after transcatheter embolisation (TCE). The aim of this study was to follow up children after TCE of aorto-pulmonary collaterals (APCs) with TCs.
MATERIALS AND METHODS: Successful TCE of 99 APCs was performed in children using 152 TCs. Chest radiographs were obtained on the day after the procedure, after 3-6 months and 9-12 months, and yearly thereafter.
RESULTS: Mean follow-up was 39.3 months. After 9-12 months, radiographs revealed a decrease in radio-opacity and reduction of coil width in 29 (37.6%) of 77 APCs. After a mean of 25 months (range 13-51 months), there was loss of visibility in 44 (57.2%) of 77 TCs and a reduction in 29 (37.6%) of 77. After a mean of 39.3 months, all TCs showed decrease or loss of radio-opacity. Exponential function predicts complete biodegradation of 95% of TCs within 10 years after TCE (r2= 0.923). After a mean of 28.4 months, repeat catheterisation was performed in 24 APCs with TCs with decreased or lost radio-opacity. Recanalisation had occurred in 58.3%.
CONCLUSIONS: Dissolution occurred in 57.2% of TCs within a mean of 25 months, and within 39.3 months all TCs showed decrease or loss of radio-opacity. Recanalisation of closed APCs occurred in 58.3%.

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Year:  2002        PMID: 12447586     DOI: 10.1007/s00247-002-0825-1

Source DB:  PubMed          Journal:  Pediatr Radiol        ISSN: 0301-0449


  10 in total

1.  Biodegradation of tungsten embolisation coils used in children.

Authors:  Irving P Wells
Journal:  Pediatr Radiol       Date:  2003-02-21

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  10 in total

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