BACKGROUND: Selection of the optimum mode of coronary revascularization should not only be directed by technical outcomes, but should also consider patients' postprocedural health status, including symptoms, functionality, and quality of life. METHODS: Health status was analyzed and compared after percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) using the Seattle Angina Questionnaire (SAQ). The SAQ was administered to 475 patients (252 PCI and 223 CABG) preprocedure and then monthly for 6 months and again at 1 year. Differences in baseline characteristics were controlled by multivariable risk adjustment, and outcomes over time were compared using repeated-measures analysis of variance. RESULTS: In-hospital, 6-and 12-month clinical outcomes were not different; however, 25% of PCI patients required at least one reintervention during the study period, compared with only 1% of CABG patients (p < 0.001). Although physical function decreased for CABG patients at 1 month (p < 0.001), it improved and was better than the PCI group by 12 months (p = 0.008). Relief of angina was greater for CABG than PCI when analyzed over time (p < 0.001), principally due to the adverse effects of restenosis in the PCI group. Multivariable analysis confirmed that CABG independently conferred greater angina relief compared with PCI (p < 0.001). At 12 months postprocedure, quality of life had improved to a greater extent for CABG than PCI (p = 0.004). CONCLUSIONS: Over 12 months of follow-up, health status was improved to a greater extent for CABG patients than for PCI patients, primarily due to the adverse influence of restenosis after PCI.
BACKGROUND: Selection of the optimum mode of coronary revascularization should not only be directed by technical outcomes, but should also consider patients' postprocedural health status, including symptoms, functionality, and quality of life. METHODS: Health status was analyzed and compared after percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) using the Seattle Angina Questionnaire (SAQ). The SAQ was administered to 475 patients (252 PCI and 223 CABG) preprocedure and then monthly for 6 months and again at 1 year. Differences in baseline characteristics were controlled by multivariable risk adjustment, and outcomes over time were compared using repeated-measures analysis of variance. RESULTS: In-hospital, 6-and 12-month clinical outcomes were not different; however, 25% of PCI patients required at least one reintervention during the study period, compared with only 1% of CABG patients (p < 0.001). Although physical function decreased for CABG patients at 1 month (p < 0.001), it improved and was better than the PCI group by 12 months (p = 0.008). Relief of angina was greater for CABG than PCI when analyzed over time (p < 0.001), principally due to the adverse effects of restenosis in the PCI group. Multivariable analysis confirmed that CABG independently conferred greater angina relief compared with PCI (p < 0.001). At 12 months postprocedure, quality of life had improved to a greater extent for CABG than PCI (p = 0.004). CONCLUSIONS: Over 12 months of follow-up, health status was improved to a greater extent for CABG patients than for PCI patients, primarily due to the adverse influence of restenosis after PCI.
Authors: Daniel B Morris; Keith G Wilson; Jennifer J Clinch; Darcy J Ammerman; Dean Fergusson; Ian D Graham; Amy J Porath; Alia Offman; Isabelle Boland; James Watters; Paul C Hébert Journal: Qual Life Res Date: 2006-06 Impact factor: 4.147
Authors: Mouin S Abdallah; Kaijun Wang; Elizabeth A Magnuson; John A Spertus; Michael E Farkouh; Valentin Fuster; David J Cohen Journal: JAMA Date: 2013-10-16 Impact factor: 56.272
Authors: Mattie J Lenzen; Wilma J M Scholte op Reimer; Susanne S Pedersen; Eric Boersma; Willibald Maier; Petr Widimsky; Maarten L Simoons; Nestor F Mercado; William Wijns Journal: Heart Date: 2006-09-15 Impact factor: 5.994
Authors: Lakshmi Venkitachalam; Kevin E Kip; Suresh R Mulukutla; Faith Selzer; Warren Laskey; James Slater; Howard A Cohen; Robert L Wilensky; David O Williams; Oscar C Marroquin; Kim Sutton-Tyrrell; Clareann H Bunker; Sheryl F Kelsey Journal: Circ Cardiovasc Qual Outcomes Date: 2009-10-13
Authors: Manfred Stommel; Ade Olomu; Margaret Holmes-Rovner; William Corser; Joseph C Gardiner Journal: BMC Health Serv Res Date: 2006-10-24 Impact factor: 2.655