Literature DB >> 12439796

Emerging patterns of hookworm infection: influence of aging on the intensity of Necator infection in Hainan Province, People's Republic of China.

Jeffrey Bethony1, Jizhang Chen, Shaoxiong Lin, Shuhua Xiao, Bin Zhan, Shangwen Li, Haichou Xue, Fuying Xing, Debbie Humphries, Wang Yan, Grace Chen, Virginia Foster, John M Hawdon, Peter J Hotez.   

Abstract

We examined risk factors associated with Necator americanus infection among persons aged > or =50 years in Hainan Province, People's Republic of China. Age and sex made the most important contributions to the variation in infection intensity (28%-30%), with age alone responsible for 27% of this variation. When stratified by 20-year age intervals, the influence of shared residence was 23% for persons aged > or =50 years and 27% for those aged <20 years, who had the highest and lowest levels of infection intensity, respectively. This points to shared residence as a means of capturing the complex relationship between aging and shared socioeconomic, environmental, and behavioral factors that influence transmission of Necator infection. None of the other 26 personal or 32 household risk factors were found to be significant. The importance of aging in Necator infection reveals an emerging public health problem among the elderly population of developing countries.

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Year:  2002        PMID: 12439796     DOI: 10.1086/344268

Source DB:  PubMed          Journal:  Clin Infect Dis        ISSN: 1058-4838            Impact factor:   9.079


  48 in total

1.  Transcriptomic analysis of hookworm Ancylostoma ceylanicum life cycle stages reveals changes in G-protein coupled receptor diversity associated with the onset of parasitism.

Authors:  James P Bernot; Gabriella Rudy; Patti T Erickson; Ramesh Ratnappan; Meseret Haile; Bruce A Rosa; Makedonka Mitreva; Damien M O'Halloran; John M Hawdon
Journal:  Int J Parasitol       Date:  2020-06-25       Impact factor: 3.981

Review 2.  Developing vaccines to combat hookworm infection and intestinal schistosomiasis.

Authors:  Peter J Hotez; Jeffrey M Bethony; David J Diemert; Mark Pearson; Alex Loukas
Journal:  Nat Rev Microbiol       Date:  2010-11       Impact factor: 60.633

Review 3.  A history of hookworm vaccine development.

Authors:  Brent Schneider; Amar R Jariwala; Maria Victoria Periago; Maria Flávia Gazzinelli; Swaroop N Bose; Peter J Hotez; David J Diemert; Jeffrey M Bethony
Journal:  Hum Vaccin       Date:  2011-11-01

4.  Epidemiology of hookworm infection in Kintampo North Municipality, Ghana: patterns of malaria coinfection, anemia, and albendazole treatment failure.

Authors:  Debbie Humphries; Emily Mosites; Joseph Otchere; Welbeck Amoani Twum; Lauren Woo; Hinckley Jones-Sanpei; Lisa M Harrison; Richard D Bungiro; Blair Benham-Pyle; Langbong Bimi; Dominic Edoh; Kwabena Bosompem; Michael Wilson; Michael Cappello
Journal:  Am J Trop Med Hyg       Date:  2011-05       Impact factor: 2.345

5.  Cellular responses and cytokine production in post-treatment hookworm patients from an endemic area in Brazil.

Authors:  S M Geiger; C L Massara; J Bethony; P T Soboslay; R Corrêa-Oliveira
Journal:  Clin Exp Immunol       Date:  2004-05       Impact factor: 4.330

Review 6.  Helminth infections: the great neglected tropical diseases.

Authors:  Peter J Hotez; Paul J Brindley; Jeffrey M Bethony; Charles H King; Edward J Pearce; Julie Jacobson
Journal:  J Clin Invest       Date:  2008-04       Impact factor: 14.808

7.  Effect of heterogeneous mixing and vaccination on the dynamics of anthelmintic resistance: a nested model.

Authors:  Lorenzo Sabatelli
Journal:  PLoS One       Date:  2010-05-18       Impact factor: 3.240

8.  Spatial and genetic epidemiology of hookworm in a rural community in Uganda.

Authors:  Rachel L Pullan; Narcis B Kabatereine; Rupert J Quinnell; Simon Brooker
Journal:  PLoS Negl Trop Dis       Date:  2010-06-15

9.  Familial aggregation of human susceptibility to co- and multiple helminth infections in a population from the Poyang Lake region, China.

Authors:  Magda K Ellis; Giovanna Raso; Yue-Sheng Li; Zhu Rong; Hong-Gen Chen; Donald P McManus
Journal:  Int J Parasitol       Date:  2007-02-27       Impact factor: 3.981

10.  Prevalence and clustering of soil-transmitted helminth infections in a tribal area in southern India.

Authors:  Saravanakumar Puthupalayam Kaliappan; Santosh George; Mark Rohit Francis; Deepthi Kattula; Rajiv Sarkar; Shantidani Minz; Venkata Raghava Mohan; Kuryan George; Sheela Roy; Sitara Swarna Rao Ajjampur; Jayaprakash Muliyil; Gagandeep Kang
Journal:  Trop Med Int Health       Date:  2013-12       Impact factor: 2.622

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