Literature DB >> 12439510

Antenatal Down syndrome screening in the United States in 2001: a survey of maternal-fetal medicine specialists.

James F X Egan1, Lillian M Kaminsky, Michael E DeRoche, Michael J Barsoom, Adam F Borgida, Peter A Benn.   

Abstract

OBJECTIVE: Our objectives were to determine patterns of antenatal Down syndrome screening and risk adjustment by maternal-fetal medicine specialists in the United States in 2001. STUDY
DESIGN: A survey to investigate Down syndrome screening practice patterns was mailed to the 1,638 members of the Society of Maternal-Fetal Medicine in the United States. Practice demographics, screening patterns, and the numeric risks quoted in counseling were analyzed.
RESULTS: Five hundred forty-three specialists (33.2%) responded; 530 of these specialists (97.6%) performed antenatal Down syndrome screening; all of them offered second-trimester screening, and 247 of them (45.5%) offered first-trimester screening. With the use of second-trimester ultrasonography, risk was increased by 69.4% of respondents and decreased by 33.1%. Amniocentesis was the most frequently used diagnostic test (83.2%), with loss rates quoted at 1:100 to 1:1,000.
CONCLUSION: Maternal-fetal medicine specialists show a wide in variation practices used for Down syndrome screening, modification of risk, and quoted procedure-related loss rates. This information calls for a consensus regarding risks that are quoted in Down syndrome counseling.

Mesh:

Year:  2002        PMID: 12439510     DOI: 10.1067/mob.2002.126980

Source DB:  PubMed          Journal:  Am J Obstet Gynecol        ISSN: 0002-9378            Impact factor:   8.661


  4 in total

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2.  Prenatal testing for Down syndrome: comparison of screening practices in the UK and USA.

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Journal:  J Genet Couns       Date:  2009-11-03       Impact factor: 2.537

3.  Biochemical Serum Markers Influencing Maternal Age Risk for Down's Syndrome in Quadruple Marker.

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4.  Comparison of different strategies in prenatal screening for Down's syndrome: cost effectiveness analysis of computer simulation.

Authors:  Jean Gekas; Geneviève Gagné; Emmanuel Bujold; Daniel Douillard; Jean-Claude Forest; Daniel Reinharz; François Rousseau
Journal:  BMJ       Date:  2009-02-13
  4 in total

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