| Literature DB >> 12435451 |
Kristina Borstnik1, Ik-hyeon Paik, Theresa A Shapiro, Gary H Posner.
Abstract
Mechanism-based rational design and gram-scale chemical synthesis have produced some new trioxane and endoperoxide antimalarial drug candidates that are efficacious and safe. This review summarises recent achievements in this area of peroxide drug development for malaria chemotherapy.Entities:
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Year: 2002 PMID: 12435451 DOI: 10.1016/s0020-7519(02)00195-9
Source DB: PubMed Journal: Int J Parasitol ISSN: 0020-7519 Impact factor: 3.981