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Literature DB >> 12434012

Regulation of chromatin remodeling by inositol polyphosphates.

David J Steger¹, Elizabeth S Haswell, Aimee L Miller, Susan R Wente, Erin K O'Shea.

Abstract

Chromatin remodeling is required for efficient transcription of eukaryotic genes. In a genetic selection for budding yeast mutants that were defective in induction of the phosphate-responsive PHO5 gene, we identified mutations in ARG82/IPK2, which encodes a nuclear inositol polyphosphate kinase. In arg82 mutant strains, remodeling of PHO5 promoter chromatin is impaired, and the adenosine triphosphate-dependent chromatin-remodeling complexes SWI/SNF and INO80 are not efficiently recruited to phosphate-responsive promoters. These results suggest a role for the small molecule inositol polyphosphate in the regulation of chromatin remodeling and transcription.

Entities: Chemical Gene Species

Mesh：

Substances：

Year: 2002 PMID： 12434012 PMCID： PMC1458531 DOI： 10.1126/science.1078062

Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728

24 in total

1. Recruitment of the yeast MADS-box proteins, ArgRI and Mcm1 by the pleiotropic factor ArgRIII is required for their stability.

Authors: M El Bakkoury; E Dubois; F Messenguy
Journal: Mol Microbiol Date: 2000-01 Impact factor: 3.501

2. Activation domain-mediated targeting of the SWI/SNF complex to promoters stimulates transcription from nucleosome arrays.

Authors: K E Neely; A H Hassan; A E Wallberg; D J Steger; B R Cairns; A P Wright; J L Workman
Journal: Mol Cell Date: 1999-10 Impact factor: 17.970

3. Global histone acetylation and deacetylation in yeast.

Authors: M Vogelauer; J Wu; N Suka; M Grunstein
Journal: Nature Date: 2000-11-23 Impact factor: 49.962

Review 4. Cooperation between complexes that regulate chromatin structure and transcription.

Authors: Geeta J Narlikar; Hua-Ying Fan; Robert E Kingston
Journal: Cell Date: 2002-02-22 Impact factor: 41.582

5. The inositol hexakisphosphate kinase family. Catalytic flexibility and function in yeast vacuole biogenesis.

Authors: A Saiardi; J J Caffrey; S H Snyder; S B Shears
Journal: J Biol Chem Date: 2000-08-11 Impact factor: 5.157

6. Inositol polyphosphate multikinase (ArgRIII) determines nuclear mRNA export in Saccharomyces cerevisiae.

Authors: A Saiardi; J J Caffrey; S H Snyder; S B Shears
Journal: FEBS Lett Date: 2000-02-18 Impact factor: 4.124

7. Modulation of ATP-dependent chromatin-remodeling complexes by inositol polyphosphates.

Authors: Xuetong Shen; Hua Xiao; Ryan Ranallo; Wei-Hua Wu; Carl Wu
Journal: Science Date: 2002-11-14 Impact factor: 47.728

8. A chromatin remodelling complex involved in transcription and DNA processing.

Authors: X Shen; G Mizuguchi; A Hamiche; C Wu
Journal: Nature Date: 2000-08-03 Impact factor: 49.962

9. The chromo domain protein chd1p from budding yeast is an ATP-dependent chromatin-modifying factor.

Authors: H G Tran; D J Steger; V R Iyer; A D Johnson
Journal: EMBO J Date: 2000-05-15 Impact factor: 11.598

10. A role for nuclear inositol 1,4,5-trisphosphate kinase in transcriptional control.

Authors: A R Odom; A Stahlberg; S R Wente; J D York
Journal: Science Date: 2000-03-17 Impact factor: 47.728

155 in total

1. Novel functions of the phosphatidylinositol metabolic pathway discovered by a chemical genomics screen with wortmannin.

Authors: Amani Zewail; Michael W Xie; Yi Xing; Lan Lin; P Fred Zhang; Wei Zou; Jonathan P Saxe; Jing Huang
Journal: Proc Natl Acad Sci U S A Date: 2003-03-03 Impact factor: 11.205

2. Inositol 1,3,4,5,6-pentakisphosphate 2-kinase is a distant IPK member with a singular inositide binding site for axial 2-OH recognition.

Authors: Beatriz González; Jose Ignacio Baños-Sanz; Maider Villate; Charles Alistair Brearley; Julia Sanz-Aparicio
Journal: Proc Natl Acad Sci U S A Date: 2010-05-07 Impact factor: 11.205

Regulation of chromatin remodeling by inositol polyphosphates.

1. Recruitment of the yeast MADS-box proteins, ArgRI and Mcm1 by the pleiotropic factor ArgRIII is required for their stability.

2. Activation domain-mediated targeting of the SWI/SNF complex to promoters stimulates transcription from nucleosome arrays.

3. Global histone acetylation and deacetylation in yeast.

Review 4. Cooperation between complexes that regulate chromatin structure and transcription.

5. The inositol hexakisphosphate kinase family. Catalytic flexibility and function in yeast vacuole biogenesis.

6. Inositol polyphosphate multikinase (ArgRIII) determines nuclear mRNA export in Saccharomyces cerevisiae.

7. Modulation of ATP-dependent chromatin-remodeling complexes by inositol polyphosphates.

8. A chromatin remodelling complex involved in transcription and DNA processing.

9. The chromo domain protein chd1p from budding yeast is an ATP-dependent chromatin-modifying factor.

10. A role for nuclear inositol 1,4,5-trisphosphate kinase in transcriptional control.

1. Novel functions of the phosphatidylinositol metabolic pathway discovered by a chemical genomics screen with wortmannin.

2. Inositol 1,3,4,5,6-pentakisphosphate 2-kinase is a distant IPK member with a singular inositide binding site for axial 2-OH recognition.

Review 3. Diabetes-induced birth defects: what do we know? What can we do?

Review 4. How versatile are inositol phosphate kinases?

5. Targeted cytosine methylation for in vivo detection of protein-DNA interactions.

6. Control of stochasticity in eukaryotic gene expression.

7. Sfp1 is a stress- and nutrient-sensitive regulator of ribosomal protein gene expression.

8. Genetic analysis of chromatin remodeling using budding yeast as a model.

9. Biography of Erin K. O'Shea.

10. Activation of the ADE genes requires the chromatin remodeling complexes SAGA and SWI/SNF.