Literature DB >> 12433979

Spatial heterogeneity in the heart: recent insights and open questions.

Ulrich K M Decking1.   

Abstract

Within the left ventricular myocardium and despite its rather homogeneous structure, local myocardial perfusion varies substantially. Areas of low and high local flow differ with regard to substrate uptake, energy turnover, and demand. This spatial heterogeneity is related to distinct differences in local protein expression, forming the basis of a novel homeostatic mechanism.

Mesh：

Year:  2002        PMID： 12433979     DOI： 10.1152/nips.01393.2002

Source DB:  PubMed          Journal:  News Physiol Sci        ISSN： 0886-1714


  10 in total

Review 1.  Theoretical models for coronary vascular biomechanics: progress & challenges.

Authors:  Sarah L Waters; Jordi Alastruey; Daniel A Beard; Peter H M Bovendeerd; Peter F Davies; Girija Jayaraman; Oliver E Jensen; Jack Lee; Kim H Parker; Aleksander S Popel; Timothy W Secomb; Maria Siebes; Spencer J Sherwin; Rebecca J Shipley; Nicolas P Smith; Frans N van de Vosse
Journal:  Prog Biophys Mol Biol       Date:  2010-10-30       Impact factor: 3.667

2.  Origins of heterogeneity in tissue perfusion and metabolism.

Authors:  Axel R Pries; Timothy W Secomb
Journal:  Cardiovasc Res       Date:  2008-11-21       Impact factor: 10.787

3.  Intrinsic cardiac adrenergic (ICA) cell density and MAO-A activity in failing rat hearts.

Authors:  Vincent W W van Eif; Sylvia J P Bogaards; Willem J van der Laarse
Journal:  J Muscle Res Cell Motil       Date:  2013-12-19       Impact factor: 2.698

4.  A quantitative pixel-wise measurement of myocardial blood flow by contrast-enhanced first-pass CMR perfusion imaging: microsphere validation in dogs and feasibility study in humans.

Authors:  Li-Yueh Hsu; Daniel W Groves; Anthony H Aletras; Peter Kellman; Andrew E Arai
Journal:  JACC Cardiovasc Imaging       Date:  2012-02

Review 5.  The shunt problem: control of functional shunting in normal and tumour vasculature.

Authors:  Axel R Pries; Michael Höpfner; Ferdinand le Noble; Mark W Dewhirst; Timothy W Secomb
Journal:  Nat Rev Cancer       Date:  2010-07-15       Impact factor: 60.716

6.  In vivo study of microcirculation in canine myocardium using the IVIM method.

Authors:  Virginie Callot; Eric Bennett; Ulrich K M Decking; Robert S Balaban; Han Wen
Journal:  Magn Reson Med       Date:  2003-09       Impact factor: 4.668

7.  Fractal properties of perfusion heterogeneity in optimized arterial trees: a model study.

Authors:  Rudolf Karch; Friederike Neumann; Bruno K Podesser; Martin Neumann; Paul Szawlowski; Wolfgang Schreiner
Journal:  J Gen Physiol       Date:  2003-08-11       Impact factor: 4.086

8.  Effects of myocardial function and systemic circulation on regional coronary perfusion.

Authors:  Ravi Namani; Lik C Lee; Yoram Lanir; Benjamin Kaimovitz; Sheikh M Shavik; Ghassan S Kassab
Journal:  J Appl Physiol (1985)       Date:  2020-02-20

9.  Na⁺ ions as spatial intracellular messengers for co-ordinating Ca²⁺ signals during pH heterogeneity in cardiomyocytes.

Authors:  Pawel Swietach; Kenneth W Spitzer; Richard D Vaughan-Jones
Journal:  Cardiovasc Res       Date:  2014-12-16       Impact factor: 10.787

10.  Native cardiac reserve predicts survival in acute post infarction heart failure in mice.

Authors:  Margareta Scharin Täng; Truls Råmunddal; Malin Lindbom; Elmir Omerovic
Journal:  Cardiovasc Ultrasound       Date:  2007-12-02       Impact factor: 2.062
  10 in total

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