Literature DB >> 12428285

Pathogenetic role of dysbacteriosis in the development of complications of type 1 diabetes mellitus in children.

G N Rozanova1, D A Voevodin, M A Stenina, M V Kushnareva.   

Abstract

A relationship between enteric microbiocenosis and severity of type 1 diabetes mellitus was detected. Microbiological analysis showed II-IV degree dysbacteriosis in all diabetic children. Long-term therapy with probiotics aimed at eradication of opportunistic microflora resulted in recovery of microbiocenosis, which was paralleled by improvement of the clinical status, regression of complications in children who were ill for a long time, and prevention of complications in children with newly detected diabetes. These results indicate the leading role of chronic enteric toxic infectious process in the development of complications of type 1 diabetes. The significance of infection in the pathogenesis of other noninfectious diseases in man is discussed.

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Year:  2002        PMID: 12428285     DOI: 10.1023/a:1015503006854

Source DB:  PubMed          Journal:  Bull Exp Biol Med        ISSN: 0007-4888            Impact factor:   0.804


  6 in total

1.  Systematic Review of the Effect of Enteral Feeding on Gut Microbiota in Preterm Infants.

Authors:  Wanli Xu; Michelle P Judge; Kendra Maas; Naveed Hussain; Jacqueline M McGrath; Wendy A Henderson; Xiaomei Cong
Journal:  J Obstet Gynecol Neonatal Nurs       Date:  2017-10-14

2.  Berberine suppresses intestinal disaccharidases with beneficial metabolic effects in diabetic states, evidences from in vivo and in vitro study.

Authors:  Li Liu; Yun-Li Yu; Jian-Song Yang; Yang Li; Yao-Wu Liu; Yan Liang; Xiao-Dong Liu; Lin Xie; Guang-Ji Wang
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2010-03-13       Impact factor: 3.000

3.  Probiotics decreased the bioavailability of the bile acid analog, monoketocholic acid, when coadministered with gliclazide, in healthy but not diabetic rats.

Authors:  Hani Al-Salami; Grant Butt; Ian Tucker; Svetlana Golocorbin-Kon; Momir Mikov
Journal:  Eur J Drug Metab Pharmacokinet       Date:  2011-08-28       Impact factor: 2.441

4.  The vaginal bacterial communities of Japanese women resemble those of women in other racial groups.

Authors:  Xia Zhou; Melanie A Hansmann; Catherine C Davis; Haruo Suzuki; Celeste J Brown; Ursel Schütte; Jacob D Pierson; Larry J Forney
Journal:  FEMS Immunol Med Microbiol       Date:  2009-10-03

5.  Comparative pharmacokinetics of baicalin, wogonoside, baicalein and wogonin in plasma after oral administration of pure baicalin, radix scutellariae and scutellariae-paeoniae couple extracts in normal and ulcerative colitis rats.

Authors:  Zhen-Qiu Zhang; Wei Liua; Li Zhuang; Jing Wang; Shuai Zhang
Journal:  Iran J Pharm Res       Date:  2013       Impact factor: 1.696

Review 6.  Is there any association between gut microbiota and type 1 diabetes? A systematic review.

Authors:  Parnian Jamshidi; Saba Hasanzadeh; Azin Tahvildari; Yeganeh Farsi; Mahta Arbabi; João Felipe Mota; Leonardo A Sechi; Mohammad Javad Nasiri
Journal:  Gut Pathog       Date:  2019-10-14       Impact factor: 4.181

  6 in total

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