Literature DB >> 12427642

Proton MR spectroscopy of Wernicke encephalopathy.

Mario Mascalchi1, Giacomo Belli, Laura Guerrini, Marco Nistri, Ines Del Seppia, Natale Villari.   

Abstract

Two patients with acute thiamine deficiency were examined with thalamic single-voxel proton MR spectroscopy. T2-weighted images exhibited increased signal intensity. N-acetylaspartate (NAA)/creatine (Cr) ratios were low without detectable lactate. Owing to substantially decreased choline (Cho) T2, the Cho/Cr ratio was not decreased. After thiamine therapy, the NAA/Cr ratio increased, paralleling clinical improvement and reduction in the areas of signal-intensity changes.

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Year:  2002        PMID: 12427642      PMCID: PMC8185837     

Source DB:  PubMed          Journal:  AJNR Am J Neuroradiol        ISSN: 0195-6108            Impact factor:   3.825


  9 in total

1.  Wernicke encephalopathy: MR findings in five patients.

Authors:  M Gallucci; A Bozzao; A Splendiani; C Masciocchi; R Passariello
Journal:  AJNR Am J Neuroradiol       Date:  1990 Sep-Oct       Impact factor: 3.825

Review 2.  Mechanisms of neuronal cell death in Wernicke's encephalopathy.

Authors:  A S Hazell; K G Todd; R F Butterworth
Journal:  Metab Brain Dis       Date:  1998-06       Impact factor: 3.584

3.  In vivo and in vitro proton NMR spectroscopic studies of thiamine-deficient rat brains.

Authors:  H Lee; G E Holburn; R R Price
Journal:  J Magn Reson Imaging       Date:  2001-02       Impact factor: 4.813

4.  Absolute quantitation of brain 1H nuclear magnetic resonance spectra. Comparison of different approaches.

Authors:  R Longo; A Bampo; R Vidimari; S Magnaldi; A Giorgini
Journal:  Invest Radiol       Date:  1995-04       Impact factor: 6.016

5.  Application of high field localised in vivo 1H MRS to study biochemical changes in the thiamin deficient rat brain under glucose load.

Authors:  S E Rose; P F Nixon; F O Zelaya; B T Wholohan; C Zimitat; L N Moxon; S Crozier; I M Brereton; D M Doddrell
Journal:  NMR Biomed       Date:  1993 Sep-Oct       Impact factor: 4.044

6.  1H chemical shift imaging reveals loss of brain tumor choline signal after administration of Gd-contrast.

Authors:  P E Sijens; M J van den Bent; P J Nowak; P van Dijk; M Oudkerk
Journal:  Magn Reson Med       Date:  1997-02       Impact factor: 4.668

7.  In vivo localized proton NMR spectroscopy of thiamine-deficient rat brain.

Authors:  H Lee; J Tarter; G E Holburn; R R Price; D D Weinstein; P R Martin
Journal:  Magn Reson Med       Date:  1995-09       Impact factor: 4.668

8.  Two types of brain lesions in Wernicke's encephalopathy.

Authors:  A Torvik
Journal:  Neuropathol Appl Neurobiol       Date:  1985 May-Jun       Impact factor: 8.090

9.  The concentration of N-acetyl aspartate, creatine + phosphocreatine, and choline in different parts of the brain in adulthood and senium.

Authors:  P Christiansen; P Toft; H B Larsson; M Stubgaard; O Henriksen
Journal:  Magn Reson Imaging       Date:  1993       Impact factor: 2.546

  9 in total
  10 in total

1.  Abnormally high levels of brain N-acetylaspartate in children with sickle cell disease.

Authors:  R Grant Steen; Robert J Ogg
Journal:  AJNR Am J Neuroradiol       Date:  2005-03       Impact factor: 3.825

Review 2.  CT and MRI of Wernicke's encephalopathy.

Authors:  A Cerase; E Rubenni; A Rufa; I Vallone; P Galluzzi; G Coratti; F Franchi; F Giannini; C Venturi
Journal:  Radiol Med       Date:  2011-01-12       Impact factor: 3.469

3.  In vivo evidence for alcohol-induced neurochemical changes in rat brain without protracted withdrawal, pronounced thiamine deficiency, or severe liver damage.

Authors:  Natalie M Zahr; Dirk Mayer; Shara Vinco; Juan Orduna; Richard Luong; Edith V Sullivan; Adolf Pfefferbaum
Journal:  Neuropsychopharmacology       Date:  2008-08-13       Impact factor: 7.853

4.  Concomitants of alcoholism: differential effects of thiamine deficiency, liver damage, and food deprivation on the rat brain in vivo.

Authors:  Natalie M Zahr; Edith V Sullivan; Torsten Rohlfing; Dirk Mayer; Amy M Collins; Richard Luong; Adolf Pfefferbaum
Journal:  Psychopharmacology (Berl)       Date:  2016-04-30       Impact factor: 4.530

5.  Associations between in vivo neuroimaging and postmortem brain cytokine markers in a rodent model of Wernicke's encephalopathy.

Authors:  Natalie M Zahr; Carsten Alt; Dirk Mayer; Torsten Rohlfing; Amy Manning-Bog; Richard Luong; Edith V Sullivan; Adolf Pfefferbaum
Journal:  Exp Neurol       Date:  2014-06-25       Impact factor: 5.330

Review 6.  Neuroimaging of Wernicke's encephalopathy and Korsakoff's syndrome.

Authors:  Young-Chul Jung; Sandra Chanraud; Edith V Sullivan
Journal:  Neuropsychol Rev       Date:  2012-05-11       Impact factor: 7.444

Review 7.  Neuroimaging in alcohol use disorder: From mouse to man.

Authors:  Michael Fritz; Anna M Klawonn; Natalie M Zahr
Journal:  J Neurosci Res       Date:  2019-04-22       Impact factor: 4.164

8.  Imaging neuroinflammation? A perspective from MR spectroscopy.

Authors:  Natalie M Zahr; Dirk Mayer; Torsten Rohlfing; Edith V Sullivan; Adolf Pfefferbaum
Journal:  Brain Pathol       Date:  2014-11       Impact factor: 6.508

Review 9.  MR imaging findings in alcoholic and nonalcoholic acute Wernicke's encephalopathy: a review.

Authors:  Gaetana Manzo; Angela De Gennaro; Attilio Cozzolino; Antonietta Serino; Giacomo Fenza; Andrea Manto
Journal:  Biomed Res Int       Date:  2014-06-24       Impact factor: 3.411

Review 10.  Alcohol's Effects on the Brain: Neuroimaging Results in Humans and Animal Models.

Authors:  Natalie M Zahr; Adolf Pfefferbaum
Journal:  Alcohol Res       Date:  2017
  10 in total

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