| Literature DB >> 12423891 |
Syuntaro Hiradate1, Shigenobu Yoshida, Hajime Sugie, Hiroshi Yada, Yoshiharu Fujii.
Abstract
Bacillus amyloliquefaciens strain RC-2 produced seven antifungal compounds (1-7) secreted into the culture filtrate. These compounds inhibited the development of mulberry anthracnose caused by the fungus, Colletotrichum dematium. Chemical structural analyses by NMR and FAB-MS revealed that all these compounds were iturins (cyclic peptides with the following sequence: L-Asn --> D-Tyr --> D-Asn --> L-Gln --> L-Pro --> D-Asn --> L-Ser --> D-beta-amino acid -->) and compounds 1-6 are identical to iturins A-2-A-7, respectively. Compound 7 (iturin A-8) is a new iturin, which has a -(CH(2))(10)CH(CH(3))CH(2)CH(3) group as a side chain in the beta-amino acid in the molecule.Entities:
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Year: 2002 PMID： 12423891 DOI： 10.1016/s0031-9422(02)00365-5
Source DB: PubMed Journal: Phytochemistry ISSN： 0031-9422 Impact factor: 4.072