Literature DB >> 12423511

Racial and ethnic composition of volunteer cord blood donors: comparison with volunteer unrelated marrow donors.

Karen K Ballen1, Julie Hicks, Bernie Dharan, Daniel Ambruso, Kenneth Anderson, Celso Bianco, Lynn Bemiller, William Dickey, Richard Lottenberg, Mary O'Neill, Mark Popovsky, Donna Skerrett, Irena Sniecinski, John R Wingard.   

Abstract

BACKGROUND: Umbilical cord blood is an alternative peripheral blood progenitor cell source for patients who need transplantation. A presumed advantage of cord blood is the ability to increase minority recruitment. STUDY DESIGN AND METHODS: The racial composition of five member cord blood banks of the National Marrow Donor Program (NMDP) was compared, representing 9020 cord blood donors with NMDP marrow donors from comparable geographic areas, representing 417,676 donors. Cord blood and marrow donors self-reported racial designations on questionnaires. Donor statistics were compared with baseline racial data of deliveries from participating hospitals for cord blood donors and with geographic census data for marrow donors.
RESULTS: The California, Florida, and Massachusetts cord blood banks recruited a lower percentage of minorities than the corresponding marrow donor centers. In New York and Colorado, minority recruitment was equivalent. In California, Florida, Massachusetts, and New York, the cord blood banks recruited a lower percentage of minorities than those delivering at the respective hospitals. The cord blood banks in California, Colorado, Florida, and Massachusetts recruited a lower percentage of minorities compared with delivery data than the corresponding marrow donor centers compared with census population (p < 0.001). In New York, the percentages were similar.
CONCLUSION: The problem of insufficient minority recruitment of cord blood has not yet been solved. Better strategies are needed to recruit minority donors.

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Year:  2002        PMID: 12423511     DOI: 10.1046/j.1537-2995.2002.00191.x

Source DB:  PubMed          Journal:  Transfusion        ISSN: 0041-1132            Impact factor:   3.157


  12 in total

1.  Biospecimen repositories: are blood donors willing to participate?

Authors:  Erik A Scott; Karen S Schlumpf; Sunitha M Mathew; Alan E Mast; Michael P Busch; Jerome L Gottschall
Journal:  Transfusion       Date:  2010-09       Impact factor: 3.157

2.  Relationship of race/ethnicity and survival after single umbilical cord blood transplantation for adults and children with leukemia and myelodysplastic syndromes.

Authors:  Karen K Ballen; John P Klein; Tanya L Pedersen; Deepika Bhatla; Reggie Duerst; Joanne Kurtzberg; Hillard M Lazarus; Charles F LeMaistre; Phillip McCarthy; Paulette Mehta; Jeanne Palmer; Michelle Setterholm; John R Wingard; Steven Joffe; Susan K Parsons; Galen E Switzer; Stephanie J Lee; J Douglas Rizzo; Navneet S Majhail
Journal:  Biol Blood Marrow Transplant       Date:  2011-11-04       Impact factor: 5.742

3.  US public cord blood banking practices: recruitment, donation, and the timing of consent.

Authors:  Sherri M Broder; Roselle S Ponsaran; Aaron J Goldenberg
Journal:  Transfusion       Date:  2012-07-15       Impact factor: 3.157

4.  Knowledge and willingness to provide research biospecimens among foreign-born Latinos using safety-net clinics.

Authors:  Christopher A Loffredo; Gheorghe Luta; Sherrie Wallington; Solomon B Makgoeng; Claire Selsky; Jeanne S Mandelblatt; Lucile L Adams-Campbell
Journal:  J Community Health       Date:  2013-08

5.  Ethnicity, length of time on the register and sex predict donor availability at the confirmatory typing stage.

Authors:  R N Lown; S G E Marsh; G E Switzer; K A Latham; J A Madrigal; B E Shaw
Journal:  Bone Marrow Transplant       Date:  2014-01-13       Impact factor: 5.483

6.  Expansion of allospecific regulatory T cells after anergized, mismatched bone marrow transplantation.

Authors:  Jeffrey K Davies; Lee M Nadler; Eva C Guinan
Journal:  Sci Transl Med       Date:  2009-10-07       Impact factor: 17.956

7.  Prostaglandin E2 enhances human cord blood stem cell xenotransplants and shows long-term safety in preclinical nonhuman primate transplant models.

Authors:  Wolfram Goessling; Robyn S Allen; Xiao Guan; Ping Jin; Naoya Uchida; Michael Dovey; James M Harris; Mark E Metzger; Aylin C Bonifacino; David Stroncek; Joseph Stegner; Myriam Armant; Thorsten Schlaeger; John F Tisdale; Leonard I Zon; Robert E Donahue; Trista E North
Journal:  Cell Stem Cell       Date:  2011-04-08       Impact factor: 24.633

Review 8.  Low dose total body irradiation followed by allogeneic lymphocyte infusion for refractory hematologic malignancy--an updated review.

Authors:  Karen K Ballen; Gerald Colvin; David Porter; Peter J Quesenberry
Journal:  Leuk Lymphoma       Date:  2004-05

9.  Age-dependent HLA profiles of the Israeli population: impact on hematopoietic cell donor recruitment and availability.

Authors:  Moshe Israeli; Machteld Oudshoorn; Geert W Haasnoot; Tirza Klein; Bracha Zisser; Gideon Bach; Frans H J Claas
Journal:  Immunogenetics       Date:  2014-10       Impact factor: 2.846

10.  Minority and foreign-born representation among US blood donors: demographics and donation frequency for 2006.

Authors:  Edward L Murphy; Beth Shaz; Christopher D Hillyer; Patricia Carey; Brian S Custer; Nora Hirschler; Junyong Fang; George B Schreiber
Journal:  Transfusion       Date:  2009-06-23       Impact factor: 3.157

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