Literature DB >> 12419365

Structure-activity relationships for a series of thiobenzamide influenza fusion inhibitors derived from 1,3,3-trimethyl-5-hydroxy-cyclohexylmethylamine.

Kuo Long Yu1, Albert F Torri, Guangxiang Luo, Christopher Cianci, Katharine Grant-Young, Stephanie Danetz, Lawrence Tiley, Mark Krystal, Nicholas A Meanwell.   

Abstract

The anti-influenza activity of a series of thiobenzamide fusion inhibitors derived from 1,3,3-trimethyl-5-hydroxy-cyclohexylmethylamine is profiled. Axial disposition of the thioamide moiety is essential for potent influenza inhibitory activity.

Entities:  

Mesh：

Substances：

Year:  2002        PMID： 12419365     DOI： 10.1016/s0960-894x(02)00761-8

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  9 in total

1.  How influenza virus is locked out of the cell.

Authors:  Yorgo Modis
Journal:  Proc Natl Acad Sci U S A       Date:  2008-11-24       Impact factor: 11.205

Review 2.  Structures of influenza A proteins and insights into antiviral drug targets.

Authors:  Kalyan Das; James M Aramini; Li-Chung Ma; Robert M Krug; Eddy Arnold
Journal:  Nat Struct Mol Biol       Date:  2010-04-11       Impact factor: 15.369

3.  ETM-ANN approach application for thiobenzamide and quinolizidine derivatives.

Authors:  M Saracoglu; F Kandemirli; V Kovalishyn; T Arslan; E E Ebenso
Journal:  J Biomed Biotechnol       Date:  2010-09-07

Review 4.  Emerging antiviral targets for influenza A virus.

Authors:  Robert M Krug; James M Aramini
Journal:  Trends Pharmacol Sci       Date:  2009-05-08       Impact factor: 14.819

Review 5.  Antiviral strategies against influenza virus: towards new therapeutic approaches.

Authors:  Arianna Loregian; Beatrice Mercorelli; Giulio Nannetti; Chiara Compagnin; Giorgio Palù
Journal:  Cell Mol Life Sci       Date:  2014-04-04       Impact factor: 9.261

6.  Structure of influenza hemagglutinin in complex with an inhibitor of membrane fusion.

Authors:  Rupert J Russell; Philip S Kerry; David J Stevens; David A Steinhauer; Stephen R Martin; Steven J Gamblin; John J Skehel
Journal:  Proc Natl Acad Sci U S A       Date:  2008-11-12       Impact factor: 11.205

Review 7.  Compounds with anti-influenza activity: present and future of strategies for the optimal treatment and management of influenza. Part II: Future compounds against influenza virus.

Authors:  R Gasparini; D Amicizia; P L Lai; N L Bragazzi; D Panatto
Journal:  J Prev Med Hyg       Date:  2014-12

Review 8.  Anti-influenza virus agents: synthesis and mode of action.

Authors:  Irene M Lagoja; Erik De Clercq
Journal:  Med Res Rev       Date:  2008-01       Impact factor: 12.944

9.  Inhibition of influenza H7 hemagglutinin-mediated entry.

Authors:  Aleksandar Antanasijevic; Han Cheng; Duncan J Wardrop; Lijun Rong; Michael Caffrey
Journal:  PLoS One       Date:  2013-10-23       Impact factor: 3.240
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.