| Literature DB >> 12419239 |
Abstract
Current models for epigenetic gene silencing envision a static relationship between histone modifications and transcription. However, evidence for nucleosome mobility and replacement favors a dynamic model that may explain phenomena ranging from variegation to the neural restriction of Rett syndrome.Entities:
Mesh:
Substances:
Year: 2002 PMID: 12419239 DOI: 10.1016/s0092-8674(02)01081-4
Source DB: PubMed Journal: Cell ISSN: 0092-8674 Impact factor: 41.582