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Literature DB >> 12418356

New directions in the pharmacotherapy of posttraumatic stress disorder.

Charles R Marmar¹, Thomas C Neylan, Frank B Schoenfeld.

Abstract

Advances in psychopharmacology of PTSD are presented, focusing on antidepressants, adrenergic agents, antianxiety agents, and mood stabilizers. Treatment recommendations are related to recent advances in the understanding of the biology of PTSD. Pharmacotherapy of PTSD in children and adolescents is discussed, including recommended dose ranges. Recommendations are specified for pharmacotherapy of trauma survivors in the immediate aftermath of traumatic exposure, and for those with acute and chronic posttraumatic stress disorders.

Entities: Disease Species

Mesh：

Substances：

Year: 2002 PMID： 12418356 DOI： 10.1023/a:1020459916113

Source DB: PubMed Journal: Psychiatr Q ISSN： 0033-2720

42 in total

1. The alpha1-adrenergic antagonist prazosin ameliorates combat trauma nightmares in veterans with posttraumatic stress disorder: a report of 4 cases.

Authors: M A Raskind; D J Dobie; E D Kanter; E C Petrie; C E Thompson; E R Peskind
Journal: J Clin Psychiatry Date: 2000-02 Impact factor: 4.384

2. Cyproheptadine for posttraumatic nightmares.

Authors: R J Rijnders; D M Laman; H Van Diujn
Journal: Am J Psychiatry Date: 2000-09 Impact factor: 18.112

3. Nightmares treated with cyproheptadine.

Authors: S Gupta; R Austin; L A Cali; V Bhatara
Journal: J Am Acad Child Adolesc Psychiatry Date: 1998-06 Impact factor: 8.829

4. Efficacy of sertraline in preventing relapse of posttraumatic stress disorder: results of a 28-week double-blind, placebo-controlled study.

Authors: J Davidson; T Pearlstein; P Londborg; K T Brady; B Rothbaum; J Bell; R Maddock; M T Hegel; G Farfel
Journal: Am J Psychiatry Date: 2001-12 Impact factor: 18.112

New directions in the pharmacotherapy of posttraumatic stress disorder.

1. The alpha1-adrenergic antagonist prazosin ameliorates combat trauma nightmares in veterans with posttraumatic stress disorder: a report of 4 cases.

2. Cyproheptadine for posttraumatic nightmares.

3. Nightmares treated with cyproheptadine.

4. Efficacy of sertraline in preventing relapse of posttraumatic stress disorder: results of a 28-week double-blind, placebo-controlled study.

5. Gabapentin in PTSD: a retrospective, clinical series of adjunctive therapy.

Review 6. Neurotransmitter alterations in PTSD: catecholamines and serotonin.

7. Imipramine treatment in pediatric burn patients with symptoms of acute stress disorder: a pilot study.

8. Fluvoxamine and sleep disturbances in posttraumatic stress disorder.

9. Posttraumatic stress disorder and quality of life: results across 64 weeks of sertraline treatment.

10. Efficacy of buspirone in the treatment of posttraumatic stress disorder: an open trial.

Review 1. Posttraumatic stress disorder in children and adolescents: a review of psychopharmacological treatment.

2. Brief report: Utility of a short screening scale for DSM-IV PTSD in primary care.

Review 3. SSRIs versus non-SSRIs in post-traumatic stress disorder: an update with recommendations.