Literature DB >> 12414780

Differential immune response to the variable surface loop antigen of P66 of Borrelia burgdorferi sensu lato species in geographically diverse populations of lyme borreliosis patients.

Katharina Ornstein1, Yngve Ostberg, Jonas Bunikis, Laila Noppa, Johan Berglund, Ragnar Norrby, Sven Bergström.   

Abstract

We have studied the immune response to a variable surface-exposed loop region of the P66 outer membrane protein from Borrelia burgdorferi sensu lato by using an enzyme immunoassay. Lyme borreliosis populations found in North America and Sweden were preferentially more seroreactive to P66 from their respective regional species, namely, B. burgdorferi sensu stricto and B. garinii and B. afzelii, respectively.

Entities:  

Mesh：

Substances：

Year:  2002        PMID： 12414780      PMCID： PMC130129          DOI： 10.1128/cdli.9.6.1382-1384.2002

Source DB:  PubMed          Journal:  Clin Diagn Lab Immunol        ISSN： 1071-412X


  18 in total

1.  Surface exposure and species specificity of an immunoreactive domain of a 66-kilodalton outer membrane protein (P66) of the Borrelia spp. that cause Lyme disease.

Authors:  J Bunikis; L Noppa; Y Ostberg; A G Barbour; S Bergström
Journal:  Infect Immun       Date:  1996-12       Impact factor: 3.441

2.  [Identification of Borrelia isolated in the USSR from Ixodes persulcatus Schulze ticks].

Authors:  V N Kriuchechnikov; E I Korenberg; S V Shcherbakov; Iu V Kovalevskiĭ; M L Levin
Journal:  Zh Mikrobiol Epidemiol Immunobiol       Date:  1988-12

3.  Molecular analysis of a 66-kDa protein associated with the outer membrane of Lyme disease Borrelia.

Authors:  J Bunikis; L Noppa; S Bergström
Journal:  FEMS Microbiol Lett       Date:  1995-09-01       Impact factor: 2.742

4.  Scored antibody reactivity determined by immunoblotting shows an association between clinical manifestations and presence of Borrelia burgdorferi sensu stricto, B. garinii, B. afzelii, and B. Valaisiana in humans.

Authors:  K Ryffel; O Péter; B Rutti; A Suard; E Dayer
Journal:  J Clin Microbiol       Date:  1999-12       Impact factor: 5.948

5.  Recognition of multiple antibody epitopes throughout Borrelia burgdorferi p66, a candidate adhesin, in patients with early or late manifestations of Lyme disease.

Authors:  H Ntchobo; H Rothermel; W Chege; A C Steere; J Coburn
Journal:  Infect Immun       Date:  2001-03       Impact factor: 3.441

Review 6.  Molecular typing of Borrelia burgdorferi sensu lato: taxonomic, epidemiological, and clinical implications.

Authors:  G Wang; A P van Dam; I Schwartz; J Dankert
Journal:  Clin Microbiol Rev       Date:  1999-10       Impact factor: 26.132

7.  Characterization of Lyme borreliosis isolates from patients with erythema migrans and neuroborreliosis in southern Sweden.

Authors:  K Ornstein; J Berglund; I Nilsson; R Norrby; S Bergström
Journal:  J Clin Microbiol       Date:  2001-04       Impact factor: 5.948

8.  Variable serum immunoglobulin responses against different Borrelia burgdorferi sensu lato species in a population at risk for and patients with Lyme disease.

Authors:  J Bunikis; B Olsén; G Westman; S Bergstroöm
Journal:  J Clin Microbiol       Date:  1995-06       Impact factor: 5.948

9.  An epidemiologic study of Lyme disease in southern Sweden.

Authors:  J Berglund; R Eitrem; K Ornstein; A Lindberg; A Ringér; H Elmrud; M Carlsson; A Runehagen; C Svanborg; R Norrby
Journal:  N Engl J Med       Date:  1995-11-16       Impact factor: 91.245

10.  Three major Lyme Borrelia genospecies (Borrelia burgdorferi sensu stricto, B. afzelii and B. garinii) identified by PCR in cerebrospinal fluid from patients with neuroborreliosis in Sweden.

Authors:  Katharina Ornstein; Johan Berglund; Sven Bergström; Ragnar Norrby; Alan G Barbour
Journal:  Scand J Infect Dis       Date:  2002
View more
  4 in total

1.  Borrelia burgdorferi HtrA: evidence for twofold proteolysis of outer membrane protein p66.

Authors:  James L Coleman; Alvaro Toledo; Jorge L Benach
Journal:  Mol Microbiol       Date:  2015-10-20       Impact factor: 3.501

2.  Broadly Protective Multivalent OspA Vaccine against Lyme Borreliosis, Developed Based on Surface Shaping of the C-Terminal Fragment.

Authors:  Abhijeet Nayak; Wolfgang Schüler; Stefan Seidel; Ivan Gomez; Andreas Meinke; Pär Comstedt; Urban Lundberg
Journal:  Infect Immun       Date:  2020-03-23       Impact factor: 3.441

3.  Whole-genome DNA array analysis of the response of Borrelia burgdorferi to a bactericidal monoclonal antibody.

Authors:  Julie M Anderton; Rafal Tokarz; Charles D Thill; Christopher J Kuhlow; Chad S Brooks; Darrin R Akins; Laura I Katona; Jorge L Benach
Journal:  Infect Immun       Date:  2004-04       Impact factor: 3.441

4.  The TamB ortholog of Borrelia burgdorferi interacts with the β-barrel assembly machine (BAM) complex protein BamA.

Authors:  Henna Iqbal; Melisha R Kenedy; Meghan Lybecker; Darrin R Akins
Journal:  Mol Microbiol       Date:  2016-09-23       Impact factor: 3.501
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.