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Literature DB >> 12413533

Genetics of autoimmune diseases in humans and in animal models.

Abstract

Recent applications of the genetic characterisation of autoimmunity in humans and in animal models have allowed the further mapping of many disease loci and, in some cases, the identification of disease genes. New approaches to the analysis of mapping, characterisation and identification of susceptibility genes have also been developed.

Entities: Disease Species

Mesh：

Year: 2002 PMID： 12413533 DOI： 10.1016/s0952-7915(02)00401-6

Source DB: PubMed Journal: Curr Opin Immunol ISSN： 0952-7915 Impact factor: 7.486

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Cited

10 in total

1. Establishment of NOD-Pdcd1-/- mice as an efficient animal model of type I diabetes.

Authors: Jian Wang; Taku Yoshida; Fumio Nakaki; Hiroshi Hiai; Taku Okazaki; Tasuku Honjo
Journal: Proc Natl Acad Sci U S A Date: 2005-08-08 Impact factor: 11.205

2. Nonobese diabetic mouse congenic analysis reveals chromosome 11 locus contributing to diabetes susceptibility, macrophage STAT5 dysfunction, and granulocyte-macrophage colony-stimulating factor overproduction.

Authors: Sally A Litherland; Kristie M Grebe; Nicole S Belkin; Edward Paek; Jessica Elf; Mark Atkinson; Laurence Morel; Michael J Clare-Salzler; Marcia McDuffie
Journal: J Immunol Date: 2005-10-01 Impact factor: 5.422

3. Autoantibodies to vascular smooth muscle are pathogenic for vasculitis.

Authors: Dana Carina Baiu; Brittany Barger; Matyas Sandor; Zsuzsa Fabry; Michael Noel Hart
Journal: Am J Pathol Date: 2005-06 Impact factor: 4.307

Review 4. Mind the gap: analysis of marker-assisted breeding strategies for inbred mouse strains.

Authors: Nicola J Armstrong; Thomas C Brodnicki; Terence P Speed
Journal: Mamm Genome Date: 2006-04-04 Impact factor: 2.957

5. Polymorphisms in interleukin-10 gene according to mutations of NOD2/CARD15 gene and relation to phenotype in Spanish patients with Crohn's disease.

Authors: Juan L Mendoza; Elena Urcelay; Raquel Lana; Alfonso Martinez; Carlos Taxonera; Emilio G de la Concha; Manuel Díaz-Rubio
Journal: World J Gastroenterol Date: 2006-01-21 Impact factor: 5.742

Genetics of autoimmune diseases in humans and in animal models.

1. Establishment of NOD-Pdcd1-/- mice as an efficient animal model of type I diabetes.

2. Nonobese diabetic mouse congenic analysis reveals chromosome 11 locus contributing to diabetes susceptibility, macrophage STAT5 dysfunction, and granulocyte-macrophage colony-stimulating factor overproduction.

3. Autoantibodies to vascular smooth muscle are pathogenic for vasculitis.

Review 4. Mind the gap: analysis of marker-assisted breeding strategies for inbred mouse strains.

5. Polymorphisms in interleukin-10 gene according to mutations of NOD2/CARD15 gene and relation to phenotype in Spanish patients with Crohn's disease.

6. Anti-interferon auto-antibodies in autoimmune polyendocrinopathy syndrome type 1.

7. Hydronephrosis associated with antiurothelial and antinuclear autoantibodies in BALB/c-Fcgr2b-/-Pdcd1-/- mice.

Review 8. Lymphopenia, Lymphopenia-Induced Proliferation, and Autoimmunity.

Review 9. Mouse models of human autoimmune diseases: essential tools that require the proper controls.

10. Systemic Lupus Erythematosus: Definitions, Contexts, Conflicts, Enigmas.