Literature DB >> 12413519

Complement in allergy and asthma.

Norma P Gerard1, Craig Gerard.   

Abstract

The complement system is a vital link between innate and adaptive immunity. Recently, several investigators have implicated the complement anaphylatoxins C3a and C5a as potential effectors in Type 1 hypersensitivity reactions, including urticaria, rhinitis and asthma. Thus, complement activation may synergize with classical IgE mediated responses, and inhibition of complement may prove therapeutic.

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Year:  2002        PMID: 12413519     DOI: 10.1016/s0952-7915(02)00410-7

Source DB:  PubMed          Journal:  Curr Opin Immunol        ISSN: 0952-7915            Impact factor:   7.486


  20 in total

Review 1.  The role of complement in danger sensing and transmission.

Authors:  Jörg Köhl
Journal:  Immunol Res       Date:  2006       Impact factor: 2.829

Review 2.  Mannan-binding lectin in asthma and allergy.

Authors:  Savneet Kaur; Steffen Thiel; P Usha Sarma; Taruna Madan
Journal:  Curr Allergy Asthma Rep       Date:  2006-09       Impact factor: 4.806

3.  Role of C5 in the development of airway inflammation, airway hyperresponsiveness, and ongoing airway response.

Authors:  Tao Peng; Liming Hao; Joseph A Madri; Xiao Su; Jack A Elias; Gregory L Stahl; Stephen Squinto; Yi Wang
Journal:  J Clin Invest       Date:  2005-05-12       Impact factor: 14.808

Review 4.  Anaphylatoxins: their role in bacterial infection and inflammation.

Authors:  Pieter-Jan Haas; Jos van Strijp
Journal:  Immunol Res       Date:  2007       Impact factor: 2.829

5.  Pre-neutralization of C5a-mediated effects by the monoclonal antibody 137-26 reacting with the C5a moiety of native C5 without preventing C5 cleavage.

Authors:  M Fung; M Lu; H Fure; W Sun; C Sun; N Y Shi; Y Dou; J Su; X Swanson; T E Mollnes
Journal:  Clin Exp Immunol       Date:  2003-08       Impact factor: 4.330

6.  Variations in the C3, C3a receptor, and C5 genes affect susceptibility to bronchial asthma.

Authors:  Koichi Hasegawa; Mayumi Tamari; Chenchen Shao; Makiko Shimizu; Naomi Takahashi; Xiao-Quan Mao; Akiko Yamasaki; Fumiaki Kamada; Satoru Doi; Hiroshi Fujiwara; Akihiko Miyatake; Kimie Fujita; Gen Tamura; Yoichi Matsubara; Taro Shirakawa; Yoichi Suzuki
Journal:  Hum Genet       Date:  2004-09       Impact factor: 4.132

Review 7.  Regulation of human mast cell and basophil function by anaphylatoxins C3a and C5a.

Authors:  Hydar Ali
Journal:  Immunol Lett       Date:  2009-11-04       Impact factor: 3.685

8.  A regulatory role for the C5a anaphylatoxin in type 2 immunity in asthma.

Authors:  Jörg Köhl; Ralf Baelder; Ian P Lewkowich; Manoj K Pandey; Heiko Hawlisch; Lihua Wang; Jennifer Best; Nancy S Herman; Alyssa A Sproles; Jörg Zwirner; Jeffrey A Whitsett; Craig Gerard; Georgia Sfyroera; John D Lambris; Marsha Wills-Karp
Journal:  J Clin Invest       Date:  2006-03       Impact factor: 14.808

Review 9.  An unexpected role for the anaphylatoxin C5a receptor in allergic sensitization.

Authors:  Bart N Lambrecht
Journal:  J Clin Invest       Date:  2006-03       Impact factor: 14.808

10.  Regulation of Toll-like receptor-mediated inflammatory response by complement in vivo.

Authors:  Xinhua Zhang; Yuko Kimura; Chongyun Fang; Lin Zhou; Georgia Sfyroera; John D Lambris; Rick A Wetsel; Takashi Miwa; Wen-Chao Song
Journal:  Blood       Date:  2007-03-15       Impact factor: 22.113

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